Diagnosis of Tuberculosis
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".
Deadline for manuscript submissions: closed (30 April 2021) | Viewed by 325
Special Issue Editors
Interests: imaging; ultrasound; magnetic resonance; radiology; computed tomography; radiography diagnostic radiology
Interests: diagnosis and treatment of the main infectious diseases with particular regard to tuberculosis; infections of the nervous system and parasitic diseases
Special Issue Information
Tuberculosis (TB) is one of the 10 most frequent causes of death in the world. Worldwide, it remains the top infectious killer, with 10 million people falling ill with TB in 2018. Tuberculosis in childhood has specific connotations that differentiate it from that of adult cases. Suspicion of tuberculosis in this category of patients may be related to clinical suspicion as well as suspected epidemiological and social suspicion. The spectrum of childhood TB varies wildly, from infection to a lung parenchymal focus (Ghon focus) with or without mediastinal lymphoadenopathy.
In addition, TB in childhood has some peculiarities: increased risk of progression from infection to disease equal to 40% in the first year of life, faster course of the disease, more prone to extrapulmonar TB including disseminated forms (miliary and tuberculous TB) and paucibacillary disease (low number of bacilli).
It’s important to know the various immunologic mechanisms which modulate individual ability to fight infection, taking into account the major host and pathogen determinants in the susceptibility to tuberculosis. Macrophages and T lymphocytes, together with granuloma formation, are the pillars of immune defense against Mtb, but however, there is no component of the immune system that does not take part in the response to this pathogen.
TB diagnosis in children is traditionally based on the tuberculin skin test (TST), chest radiography, and microbiological testing.
Dr. Paolo Toma
Dr. Laura Lancella
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- epidemiology
- screening
- risk factors
- infection
- disease
- TST
- clinical manifestation
- pathogenesis
- immunology
- genetic susceptibility to mycobacterial infections
- IFN-γ release assays
- microbiology
- GeneXpert MTB/RIF
- culture
- imaging
- ultrasound
- magnetic resonance
- radiology
- computed tomography
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
