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Diagnostics
Special Issues
Recent Advances in Diagnosis and Management of Breast Cancer
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Recent Advances in Diagnosis and Management of Breast Cancer

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 30 April 2026 | Viewed by 620

Special Issue Editor

Dr. Wing Lok Wendy Chan

E-Mail Website
Guest Editor
Department of Clinical Oncology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong
Interests: radiation dosimetric studies on breast cancer and upper gastrointestinal caner

Special Issue Information

Dear Colleagues,

In this Special Issue, we aim to highlight the latest developments in breast cancer research, diagnostic tools, and treatment strategies. With advancements in imaging techniques, such as 3D mammography and MRI, the earlier and more accurate detection of breast cancers is now possible. The incorporation of genetic profiling and biomarker analysis has revolutionized personalized treatment plans, enabling targeted therapies that improve patient outcomes. Additionally, this Special Issue will discuss the role of immunotherapy and novel drug combinations in managing advanced breast cancer cases. Cutting-edge surgical techniques and the importance of multidisciplinary care will also be emphasized, ensuring the holistic management of patients. By showcasing recent studies and clinical trials, this Special Issue will provide clinicians and researchers with valuable insights into enhancing breast cancer diagnostics and therapeutic approaches.

Dr. Wing Lok Wendy Chan
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • breast cancer
  • diagnosis
  • treatment
  • personalized medicine
  • imaging techniques
  • immunotherapy

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

14 pages, 1021 KB  
Article
Preoperative Predictors of Subsequent Breast Cancer Events Detected on Abbreviated MRI in Patients with Early-Stage Breast Cancer
by Na Lae Eun, Ji Hyun Youk, Jeong-Ah Kim, Yoon Jin Cha, Soong June Bae, Sung Gwe Ahn, Joon Jeong, Hyejin Yang, Hye Sun Lee and Eun Ju Son
Diagnostics 2025, 15(23), 2953; https://doi.org/10.3390/diagnostics15232953 - 21 Nov 2025
Viewed by 345
Abstract
Background/Objectives: This study aimed to investigate the preoperative clinicopathologic and imaging features associated with subsequent breast cancer events detected on postoperative abbreviated MRI in early-stage breast cancer patients following breast and axillary surgery. Methods: A retrospective analysis was conducted on 1171 patients [...] Read more.
Background/Objectives: This study aimed to investigate the preoperative clinicopathologic and imaging features associated with subsequent breast cancer events detected on postoperative abbreviated MRI in early-stage breast cancer patients following breast and axillary surgery. Methods: A retrospective analysis was conducted on 1171 patients (median age, 53 years; range, 24–90 years) diagnosed with clinical stage I or II breast cancer between January 2013 and December 2017. Logistic regression analysis was used to evaluate preoperative imaging features—including breast density assessed on mammography and MRI descriptors—along with clinicopathologic characteristics, to identify factors independently associated with subsequent breast cancer events during abbreviated MRI screening. Results: Among the patients, 57 (4.9%) experienced subsequent breast cancer events at a median follow-up of 74 months. In the multivariable analysis, high nuclear grade (odds ratio [OR] = 2.821; 95% confidence interval [CI], 1.427–5.577; p = 0.003), dense breast tissue on mammography (OR = 4.680; 95% CI, 1.113–19.684; p = 0.035), and absence of heterogeneous internal enhancement on preoperative MRI (OR = 0.429; 95% CI, 0.206–0.891; p = 0.023) were independently associated with subsequent breast cancer events detected using an abbreviated breast MRI protocol. Age ≥ 40 years (OR = 0.448; 95% CI, 0.193–1.039; p = 0.061) and clinical T2 stage (OR = 1.744; 95% CI, 0.969–3.139; p = 0.064) showed borderline significance. Conclusions: High nuclear grade, dense breast tissue on mammography, and absence of heterogeneous internal enhancement on preoperative MRI were associated with an increased risk of subsequent breast cancer events in patients undergoing abbreviated MRI surveillance following surgery for early-stage breast cancer. Full article
(This article belongs to the Special Issue Recent Advances in Diagnosis and Management of Breast Cancer)
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