Oral Medicine

A special issue of Dentistry Journal (ISSN 2304-6767).

Deadline for manuscript submissions: closed (31 August 2020) | Viewed by 24311

Special Issue Editors


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Guest Editor
Department of Oral Medicine, School of Dental Medicine University of Zagreb, Zagreb, Croatia
Interests: recurrent aphthous ulcers; oral lichen planus; burning mouth syndrome; oral cancer; oral adverse reaction to drugs

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Co-Guest Editor
Department of Oral Medicine, University Clinical Hospital Center Zagreb, 10000 Zagreb, Croatia
Interests: oral lichen planus; oral cancer; burning mouth syndrome

Special Issue Information

This Special Issue on the subject of oral medicine will publish new information on the diagnostic and therapeutic possibilities in common oral diseases, such as recurrent aphthous ulcers, oral lichen planus, burning mouth syndrome, oral cancer, and adverse oral reactions to drugs.

Prof. Dr. Vanja Vučićević Boras
Guest Editor

Manuscript Submission Information

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Keywords

  • recurrent aphthous ulcers,
  • oral lichen planus,
  • burning mouth syndrome,
  • oral cancer,
  • oral adverse reaction to drugs

Published Papers (5 papers)

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Research

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9 pages, 423 KiB  
Article
Association between Vitamin D and Candida-Associated Denture Stomatitis
by Miranda Muhvić-Urek, Ema Saltović, Alen Braut and Daniela Kovačević Pavičić
Dent. J. 2020, 8(4), 121; https://doi.org/10.3390/dj8040121 - 21 Oct 2020
Cited by 12 | Viewed by 2892
Abstract
Candida-associated denture stomatitis (CADS) is a fungal infection affecting 60–65% of denture wearers. Its etiology is complex and multifactorial and often associated with host immunodeficiency. Evidence exists that vitamin D has potential immunomodulatory and anti-inflammatory effects. The aim of this case–control study [...] Read more.
Candida-associated denture stomatitis (CADS) is a fungal infection affecting 60–65% of denture wearers. Its etiology is complex and multifactorial and often associated with host immunodeficiency. Evidence exists that vitamin D has potential immunomodulatory and anti-inflammatory effects. The aim of this case–control study was to assess the association between vitamin D levels and CADS. The study included 32 complete denture wearers with CADS and 32 sex- and age-matched complete denture wearers without CADS. The patients were clinically examined, and the severity of denture stomatitis was assessed according to Newton’s classification scale. The serum vitamin D level was determined via the use of an electrochemiluminescence assay. The vitamin D level in the CADS group and control group was 54.68 ± 17.07 and 56.82 ± 17.75 nmol/L, respectively. There was no significant difference between the groups (p = 0.622). Univariate logistic regression analysis showed that the presence of CADS was not associated with hypovitaminosis D (odds ratio (OR) = 1.44; 95% confidence interval (CI) = 0.37–5.54). It can be concluded that vitamin D is not associated with CADS and does not play a significant role in host susceptibility to CADS. This finding suggests that vitamin D screening is not indicated routinely in patients with Candida-associated denture stomatitis. Full article
(This article belongs to the Special Issue Oral Medicine)
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12 pages, 241 KiB  
Article
Association between Clinical Signs of Oral Lichen Planus and Oral Health-Related Quality of Life: A Preliminary Study
by Sasirin Yiemstan, Sudaduang Krisdapong and Pornpan Piboonratanakit
Dent. J. 2020, 8(4), 113; https://doi.org/10.3390/dj8040113 - 4 Oct 2020
Cited by 10 | Viewed by 2393
Abstract
Subjective patient’s symptoms and Oral Health-Related Quality of Life (OHRQoL) are recommended to be involved in oral lichen planus (OLP) studies. This study aims to assess the OHRQoL of OLP patients, and their associations with pain and OLP in Thai patients. Sixty-nine patients [...] Read more.
Subjective patient’s symptoms and Oral Health-Related Quality of Life (OHRQoL) are recommended to be involved in oral lichen planus (OLP) studies. This study aims to assess the OHRQoL of OLP patients, and their associations with pain and OLP in Thai patients. Sixty-nine patients were interviewed using the Numeric Rating Scale (NRS) for pain perception and Oral Impacts on Daily Performance (OIDP) index. OLP signs examined included localization, types, number of affected sides and clinical severity using the Thongprasom sign scoring system. There were significant associations (rs = 0.490, p < 0.001) between clinical severity and the intensity of oral impacts as well as pain (rs = 0.298, p = 0.013). The intensity of oral impacts and pain increased according to the increasing OLP clinical severity, except for the white striae lesions (Thongprasom sign score 1). The erosive/ulcerative OLP lesions (Thongprasom sign scores 4 and 5) were the most painful symptom and had the highest degree of oral impacts (p < 0.001). No significant associations were found between the number of affected lesion sides and OHRQoL (p = 0.316) and pain (p = 0.284). OHRQoL was associated with OLP type and clinical severity but not with the number of affected sides. Full article
(This article belongs to the Special Issue Oral Medicine)
7 pages, 218 KiB  
Article
Salivary Hormones and Quality of Life in Female Postmenopausal Burning Mouth Patients—A Pilot Case-Control Study
by Božana Lončar-Brzak, Valentina Vidranski, Ana Andabak-Rogulj, Danica Vidović-Juras, Ivana Todorić-Laidlaw, Dragana Gabrić and Ivana Škrinjar
Dent. J. 2020, 8(4), 111; https://doi.org/10.3390/dj8040111 - 1 Oct 2020
Cited by 7 | Viewed by 2452
Abstract
The objective of our study was to investigate salivary levels of estradiol, progesterone and dehydroepiandrosterone (DHEA), and quality of life, in female postmenopausal women with burning mouth syndrome. The study included new patients diagnosed with burning mouth syndrome and excluded local and systemic [...] Read more.
The objective of our study was to investigate salivary levels of estradiol, progesterone and dehydroepiandrosterone (DHEA), and quality of life, in female postmenopausal women with burning mouth syndrome. The study included new patients diagnosed with burning mouth syndrome and excluded local and systemic causes. Unstimulated saliva samples were taken in the morning from 9 AM and 11 AM and immediately frozen for hormone analysis. The patients filled out a self-perceived quality of life questionnaire Oral Health Impact Profile-14 and determined the intensity of mucosal symptoms according to the visual-analog scale grading 0 to 10. A total of 40 patients were included. The study group had significantly lower levels of salivary estradiol. No difference was observed in levels of progesterone and DHEA between the groups. The levels of salivary hormones did not exhibit a significant correlation according to the Spearman correlation test with a self-perceived quality of life questionnaire (OHIP-14) in the study group or in the control group. Further research on a larger number of patients is needed to verify these results. This information might help to enable more precise and efficient treatment. Full article
(This article belongs to the Special Issue Oral Medicine)
4 pages, 183 KiB  
Communication
Salivary Cortisol Levels in Patients with Oral Lichen Planus—A Pilot Case-Control Study
by Ivana Skrinjar, Valentina Vidranski, Bozana Loncar Brzak, Danica Vidovic Juras, Ana Andabak Rogulj, Vlaho Brailo and Vanja Vucicevic Boras
Dent. J. 2019, 7(2), 59; https://doi.org/10.3390/dj7020059 - 1 Jun 2019
Cited by 5 | Viewed by 3048
Abstract
It is known that cortisol level increases in stress situations. The aim of the study was to measure the levels of salivary cortisol in patients with oral lichen planus (OLP) and healthy controls. This was a case-control pilot study which included seven patients [...] Read more.
It is known that cortisol level increases in stress situations. The aim of the study was to measure the levels of salivary cortisol in patients with oral lichen planus (OLP) and healthy controls. This was a case-control pilot study which included seven patients with reticular (non-symptomatic) OLP, eight patients with atrophic/erosive (symptomatic) OLP, and nine healthy controls. We hypothesized that patients with an atrophic/erosive type of OLP have higher levels of cortisol compared to patients with the reticular type of OLP and healthy controls. In each participant, unstimulated saliva was collected in order to determine cortisol levels by using commercially available ELISA kit. Our results have shown no differences between levels of salivary cortisol in OLP patients and healthy controls. We can conclude that further research with a larger number of OLP patients is needed to determine the correlation between OLP and stress. Full article
(This article belongs to the Special Issue Oral Medicine)

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5 pages, 2088 KiB  
Case Report
Idiopathic Exposed Bone Lesions of the Jaw
by Božana Lončar Brzak, Vanja Vučičević Boras, Ana Kotarac Knežević, Mato Sušić, Sven Seiwerth and Dragana Gabrić
Dent. J. 2019, 7(2), 55; https://doi.org/10.3390/dj7020055 - 1 Jun 2019
Cited by 2 | Viewed by 12989
Abstract
Introduction: Osteonecrosis of the jaw is defined as exposed bone in the oral cavity that does not heal longer than eight weeks after identification. The two most common predisposing factors for osteonecrosis of the jaw are medication-related and radiotherapy. Rarely, exposed bone in [...] Read more.
Introduction: Osteonecrosis of the jaw is defined as exposed bone in the oral cavity that does not heal longer than eight weeks after identification. The two most common predisposing factors for osteonecrosis of the jaw are medication-related and radiotherapy. Rarely, exposed bone in the maxillofacial region can occur due to other causes and represents a clinical and therapeutic challenge for the dentist because there is no universally accepted treatment protocol. Case presentation: We report a case of a patient with two idiopathic lesions of exposed bone which have healed after systemic antibiotic therapy, seven weeks after the first examination. Conclusion: Exposed bone lesions of the jaw are a rare entity and are poorly documented in the literature. It is necessary to exclude possible local or systemic contributing factors. Surgical and conservative therapy (antibiotics) are the treatment of choice. Full article
(This article belongs to the Special Issue Oral Medicine)
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