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Article

Salivary Hormones and Quality of Life in Female Postmenopausal Burning Mouth Patients—A Pilot Case-Control Study

1
Department of Oral Medicine, School of Dental Medicine, University of Zagreb, 10000 Zagreb, Croatia
2
Department of Nuclear Medicine and Oncology, University Clinical Hospital Sisters of Mercy, 10000 Zagreb, Croatia
3
Department of Oral Medicine, University Clinical Hospital Zagreb, 10000 Zagreb, Croatia
4
Department of Psychotic Disorders (for Women), University Psychiatric Hospital Vrapce, 10000 Zagreb, Croatia
5
Department of Oral Surgery, School of Dental Medicine, University of Zagreb, 10000 Zagreb, Croatia
*
Author to whom correspondence should be addressed.
Dent. J. 2020, 8(4), 111; https://doi.org/10.3390/dj8040111
Received: 6 September 2020 / Revised: 21 September 2020 / Accepted: 23 September 2020 / Published: 1 October 2020
(This article belongs to the Special Issue Oral Medicine)
The objective of our study was to investigate salivary levels of estradiol, progesterone and dehydroepiandrosterone (DHEA), and quality of life, in female postmenopausal women with burning mouth syndrome. The study included new patients diagnosed with burning mouth syndrome and excluded local and systemic causes. Unstimulated saliva samples were taken in the morning from 9 AM and 11 AM and immediately frozen for hormone analysis. The patients filled out a self-perceived quality of life questionnaire Oral Health Impact Profile-14 and determined the intensity of mucosal symptoms according to the visual-analog scale grading 0 to 10. A total of 40 patients were included. The study group had significantly lower levels of salivary estradiol. No difference was observed in levels of progesterone and DHEA between the groups. The levels of salivary hormones did not exhibit a significant correlation according to the Spearman correlation test with a self-perceived quality of life questionnaire (OHIP-14) in the study group or in the control group. Further research on a larger number of patients is needed to verify these results. This information might help to enable more precise and efficient treatment. View Full-Text
Keywords: burning mouth syndrome; salivary hormones; quality of life burning mouth syndrome; salivary hormones; quality of life
MDPI and ACS Style

Lončar-Brzak, B.; Vidranski, V.; Andabak-Rogulj, A.; Vidović-Juras, D.; Todorić-Laidlaw, I.; Gabrić, D.; Škrinjar, I. Salivary Hormones and Quality of Life in Female Postmenopausal Burning Mouth Patients—A Pilot Case-Control Study. Dent. J. 2020, 8, 111. https://doi.org/10.3390/dj8040111

AMA Style

Lončar-Brzak B, Vidranski V, Andabak-Rogulj A, Vidović-Juras D, Todorić-Laidlaw I, Gabrić D, Škrinjar I. Salivary Hormones and Quality of Life in Female Postmenopausal Burning Mouth Patients—A Pilot Case-Control Study. Dentistry Journal. 2020; 8(4):111. https://doi.org/10.3390/dj8040111

Chicago/Turabian Style

Lončar-Brzak, Božana, Valentina Vidranski, Ana Andabak-Rogulj, Danica Vidović-Juras, Ivana Todorić-Laidlaw, Dragana Gabrić, and Ivana Škrinjar. 2020. "Salivary Hormones and Quality of Life in Female Postmenopausal Burning Mouth Patients—A Pilot Case-Control Study" Dentistry Journal 8, no. 4: 111. https://doi.org/10.3390/dj8040111

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