Special Issue "Oral Hygiene and Biofilms in Orthodontics"

A special issue of Dentistry Journal (ISSN 2304-6767). This special issue belongs to the section "Dental Materials".

Deadline for manuscript submissions: 30 January 2020.

Special Issue Editors

Guest Editor
Prof. Dr. Gianrico Spagnuolo Website E-Mail
Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Napoli, Italy
Interests: dental materials; dental surgery; restorative dentistry and endodontics
Guest Editor
Prof. Peter Mei Website E-Mail
Discipline of Orthodontics, Department of Oral Sciences, University of Otago
Interests: biofilm, orthodontics, caries, oral microbiome, enamel demineralization

Special Issue Information

Dear Colleagues,

This Special Issue invites submissions with a focus on orthodontics and advances in oral hygiene and biofilms.

Orthodontic fixed appliances interfere with tooth brushing and facilitate accumulation of dental biofilm (plaque). Failure to maintain good oral hygiene during orthodontic treatment can result in adverse effects such as enamel demineralization, gingivitis, and halitosis. Biofilm control in patients wearing orthodontic fixed appliances is therefore of paramount importance. Moreover, the type and the surface proprieties of orthodontic materials can play a significant role in bacterial adhesion and dental biofilm accumulation.

In order to capture the diverse knowledge and experience in this field, we encourage submissions across a range of dental research disciplines. We seek a mix of quality manuscripts: these may include original dental research and review manuscripts on key topics of interest.

Prof. Dr. Gianrico Spagnuolo
Prof. Peter Mei
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dentistry Journal is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • orthodontics
  • biofilm
  • oral hygiene
  • enamel demineralization
  • enamel remineralization
  • oral microbiome
  • dental plaque
  • orthodontic materials

Published Papers (1 paper)

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Open AccessArticle
Polyphenols Inhibit Candida albicans and Streptococcus mutans Biofilm Formation
Dent. J. 2019, 7(2), 42; https://doi.org/10.3390/dj7020042 - 11 Apr 2019
Background: Streptococcus mutans (S. mutans) and Candida albicans (C. albicans) are two major contributors to dental caries. They have a symbiotic relationship, allowing them to create an enhanced biofilm. Our goal was to examine whether two natural polyphenols (Padma [...] Read more.
Background: Streptococcus mutans (S. mutans) and Candida albicans (C. albicans) are two major contributors to dental caries. They have a symbiotic relationship, allowing them to create an enhanced biofilm. Our goal was to examine whether two natural polyphenols (Padma hepaten (PH) and a polyphenol extraction from green tea (PPFGT)) could inhibit the caries-inducing properties of S. mutans and C. albicans. Methods: Co-species biofilms of S. mutans and C. albicans were grown in the presence of PH and PPFGT. Biofilm formation was tested spectrophotometrically. Exopolysaccharides (EPS) secretion was quantified using confocal scanning laser microscopy. Biofilm development was also tested on orthodontic surfaces (Essix) to assess biofilm inhibition ability on such an orthodontic appliance. Results: PPFGT and PH dose-dependently inhibited biofilm formation without affecting the planktonic growth. We found a significant reduction in biofilm total biomass using 0.625 mg/mL PPFGT and 0.16 mg/mL PH. A concentration of 0.31 mg/mL PPFGT and 0.16 mg/mL PH inhibited the total cell growth by 54% and EPS secretion by 81%. A reduction in biofilm formation and EPS secretion was also observed on orthodontic PVC surfaces. Conclusions: The polyphenolic extractions PPFGT and PH have an inhibitory effect on S. mutans and C. albicans biofilm formation and EPS secretion. Full article
(This article belongs to the Special Issue Oral Hygiene and Biofilms in Orthodontics)
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