Special Issue "Advances in Films and Coatings for Biomedical Application"

A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Surface Coatings for Biomedicine and Bioengineering".

Deadline for manuscript submissions: 30 September 2023 | Viewed by 1048

Special Issue Editors

Dr. Evgeniia S. Vikulova
E-Mail Website
Guest Editor
Nikolaev Institute of Inorganic Chemistry, Siberian Branch of Russian Academy of Sciences, Novosibirsk 630090, Russia
Interests: film materials; coatings; composite materials; metal-organic chemical vapor deposition; noble metals; silver; magnesium; medical implamts; medical electrodes
Dr. David Sergeevichev
E-Mail Website
Guest Editor
“E.Meshalkin National Medical Research Center” of the Ministry of Health of the Russian Federation, 15, Rechkunovskaya st., Novosibirsk 630055, Russia
Interests: preclinical studies in cardiology; models of cardiovascular pathology; regenerative medicine; tissue engineering

Special Issue Information

Dear Colleagues,

The development of materials for biomedicine is one of the most important trends in modern material science. The application of films and coatings here presents an attractive way to modify the surface of biomedical products to improve their characteristics, such as biocompatibility, osseo- and tissue integration, corrosion resistance, electrochemical properties, and others. Moreover, such an approach makes it possible to impart new additional properties to a traditional bulk biomaterial; for example, the antibacterial or antifungal ones. Permanent and biodegradable materials are in demand in the relevant fields of biomedicine.

Advances in nanotechnology make it possible to obtain a variety of films and coatings, including metal, oxide, ceramic, glass, polymer, organic layers, and nano-objects (nanoparticles, nanotubes, etc.). Specially designed composite and hybrid materials are of particular interest here. Understanding the mechanisms behind the desired enhanced functional response of surface materials is the key to the development of this substantial field.

In this Special Issue, we invite researchers to share their progress in all areas of film material development for biomedical applications. The focus of the SI includes, but not limited to, the following points:

  • New ideas in design of surface materials for biomedical application including both theoretical and experimental researches;
  • Recent advances in film and coating preparation;
  • Recent advances in materials for biomedical films and coatings;
  • Recent advances in mechanisms of functional response;
  • Recent advances in clinical application of biomedical coatings.

Thematic reviews covering a specific area of this vast scientific field are warmly welcome.

Dr. Evgeniia S. Vikulova
Dr. David Sergeevichev
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • coatings
  • thin films
  • medical application
  • biological properties

Published Papers (1 paper)

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Research

Article
Biochip Surfaces Containing Recombinant Cell-Binding Domains of Fibronectin
Coatings 2022, 12(7), 880; https://doi.org/10.3390/coatings12070880 - 21 Jun 2022
Viewed by 800
Abstract
Surface immobilization and characterization of the functional activity of fibronectin (Fn) type-III domains are reported. The domains FnIII9-10 or FnIII10 containing the RGD loop and PHSRN synergy site were recombinantly produced and covalently bound to chemically activated PEG methacrylate (MA) hydrogel coatings by [...] Read more.
Surface immobilization and characterization of the functional activity of fibronectin (Fn) type-III domains are reported. The domains FnIII9-10 or FnIII10 containing the RGD loop and PHSRN synergy site were recombinantly produced and covalently bound to chemically activated PEG methacrylate (MA) hydrogel coatings by microcontact printing. Such fabricated biochip surfaces were 6 mm in diameter and consisted of 190 µm wide protein stripes separated by 200 µm spacing. They were analyzed by imaging null ellipsometry, atomic force microscopy and fluorescence microscopy. Also, the coatings were tested in human foreskin fibroblast and HeLa cultures for at least 96 h, thus evaluating their suitability for controlled cell adhesion and proliferation. However, while HeLa cultures were equally well responsive to the FnIII9-10, FnIII10 and Fn surfaces, the fibroblasts displayed lower cell and lower focal adhesion areas, as well as lower proliferation rates on the Fn fragment surfaces as compared to Fn. Nevertheless, full functional activity of the fibroblasts was confirmed by immunostaining of Fn produced by the cells adherent on the biochip surfaces. The observed interaction differences that were either cell type or surface composition-dependent demonstrate the potential use of specifically engineered Fn and other ECM protein-derived domains in biochip architectures. Full article
(This article belongs to the Special Issue Advances in Films and Coatings for Biomedical Application)
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