Surface Engineering of Bone Implants

A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Surface Coatings for Biomedicine and Bioengineering".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 1480

Special Issue Editors


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Guest Editor
Faculty of Exact and Natural Sciences, University of Reims Champagne-Ardenne, Moulin de la Housse Campus, BP 1039, CEDEX, 51687 Reims, France
Interests: electrochemistry; PVD; CVD; biomaterials; coatings; calcium phosphate; oxides; bioglass; bone implants; corrosion
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Institut de Thermique, Mécanique et Matériaux (ITheMM), Université de Reims Champagne-Ardenne (URCA), Reims, France
Interests: electrochemical deposition; electrophoretic deposition; biomaterials; prosthetic coatings; calcium phosphates; bioactive glasses; bone substitutes; electron microscopy; X-ray microanalysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The continuous aging of the worldwide population requires the development of innovative bone implants with the ability to repair or replace the functions of bone tissue. Implanted materials need specific biological, chemical, and mechanical surface properties for appropriate interactions with the body environment. Bone implants can be made of biocompatible metal, polymer, bioglass, or ceramic materials or a composite of these materials. Surface engineering, either by coating or surface treatment, is used to improve their surface properties, e.g., their bioactivity, biomechanical compatibility, topography, wettability, corrosion behavior, bone cell adhesion and growth, protein adsorption, etc. Relevant modern developments also include surface engineering that provides anti-inflammatory and antibacterial properties to the surface of bone implants.

Within this framework, this Special Issue aims to present the latest developments in this field.

Research topics of interest include, but are not limited to, the following:

  • Advanced biomaterials;
  • Bioactive thin films and coatings;
  • Hard tissue repair and regeneration;
  • The functionalization of biomaterials;
  • Bone implants with enhanced biological properties;
  • Bone implants with enhanced mechanical properties.

Dr. Richard Drevet
Prof. Hicham Benhayoune
Guest Editors

Manuscript Submission Information

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Keywords

  • surface
  • bone implant
  • bioactivity
  • biocompatibility
  • biomaterials
  • hard tissue repair
  • skeleton
  • biomedical

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Published Papers (1 paper)

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Review

29 pages, 2541 KB  
Review
Recent Advances in pH-Responsive Coatings for Orthopedic and Dental Implants: Tackling Infection and Inflammation and Enhancing Bone Regeneration
by Reyhaneh Gholami, Naser Valipour Motlagh, Zahra Yousefi, Fahimeh Gholami, Joseph J. Richardson, Behnam Akhavan, Vahid Adibnia and Vi Khanh Truong
Coatings 2025, 15(12), 1471; https://doi.org/10.3390/coatings15121471 - 12 Dec 2025
Viewed by 974
Abstract
Bone is a structurally complex and dynamic tissue that plays a crucial role in mobility and skeletal stability. However, conditions such as osteoporosis, osteoarthritis, trauma-induced fractures, infections, and malignancies often necessitate the use of orthopedic and dental implants. Despite significant progress in implant [...] Read more.
Bone is a structurally complex and dynamic tissue that plays a crucial role in mobility and skeletal stability. However, conditions such as osteoporosis, osteoarthritis, trauma-induced fractures, infections, and malignancies often necessitate the use of orthopedic and dental implants. Despite significant progress in implant biomaterials, challenges such as bacterial infection, inflammation, and loosening continue to compromise implant longevity, frequently leading to revision surgeries and extended recovery times. Smart coatings have emerged as a next-generation solution to these problems by providing on-demand, localized therapeutic responses to microenvironmental changes around implants and promoting bone regeneration. Such coatings can minimize antibiotic resistance by enabling controlled, stimulus-triggered drug release. Although the idea of using pH-sensitivity as a tool to make smart coatings is not a new thought, there are no options currently good enough to enter clinical studies. This review provides a comprehensive overview of recent advances in pH-sensitive polymers, hybrid composites, porous architectures, and bioactive linkers designed to dynamically respond to pathological pH variations at implant sites. By investigating the mechanisms of action, antibacterial and anti-inflammatory effects, and roles in bone regeneration, it is shown that the ability to provide time-dependent drug release for both short-term and long-term infections, as well as keeping the environment welcoming to the bone cell growth and replacement, is not an easy goal to reach, even with a fully biocompatable, non-toxic, and semi-biodegradable (one that releases the drug, but does not fade away) coating material compound. Reviewing all available options, including their functions and failures, finally, emerging trends, translational barriers, and future opportunities for clinical implementation are highlighted, underscoring the transformative potential of bioresponsive coatings in orthopedic and dental implant technologies. Full article
(This article belongs to the Special Issue Surface Engineering of Bone Implants)
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