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Advances in Antibacterial and Antivirus Materials and Coatings: From Fundamentals...
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Advances in Antibacterial and Antivirus Materials and Coatings: From Fundamentals to Application

A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Surface Coatings for Biomedicine and Bioengineering".

Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 3638

Special Issue Editor

Dr. Jeon Geon Han

E-Mail Website
Guest Editor
Emeritus Professor, School of Applied Material Sciences and Engineering, Sungkyunkwan University, 300 ChunChun-dong, Jangan-gu, Suwon 440 746, Republic of Korea
Interests: thin films; bio and nano films; magnetron sputtering; PECVD; plasm a surface functionalization
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

It is well known that the transmission and spread of infection have the potential to lead to global pandemics such as COVID-19, which can seriously affect both human health and the economy and lead to significant loss of human lives. Pathogens including harmful bacteria and viruses are normally active on various surfaces, such as metals, plastics, fabrics, and other combined surfaces, and are transmitted to the human body through various contacts in our daily life. Due to the COVID-19 pandemic, there was a significant increase in attention among the global community to technological developments for the mitigation and protection against pathogens, including harmful bacteria species and viruses.

Indeed, a significant amount of research has been carried out in the last few years, foucins on the protection against and control of harmful pathogens through various approaches, e.g., the development of organic and inorganic materials for killing bacteria and viruses, surface texturing protecting against the attachment of bacteria and viruses, or the release of antibiotics. Application of these approaches is also expanding to a variety of fields beyond the medical industry, such as packaging for long term storage not just for pharmaceutical medicines, but also for food and agricultural products. Advances in the development of process technology are also expected to assist in such efforts.

This Special Issue cordially invites articles focusing on recently developed organic and inorganic materials using a nano or quantum structure, thin film or bulk protecting against pathogens such as harmful bacteria, fungi, and viruses, surface coating technology, and their application in the industrial fields. In addition, papers focusing on assessment of the safety or toxicity of materials for industrial application are also solicited.

Dr. Jeon Geon Han
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antibacterial and surface coatings
  • antiviral materials and surface coatings
  • pathogen control
  • plasma and related processes
  • application of antibacterial and antiviral coatings

Published Papers (2 papers)

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Research

17 pages, 8388 KiB  
Article
Production and Characterization of Graphene Oxide Surfaces against Uropathogens
by Samuel Belo, Francisca Sousa-Cardoso, Rita Teixeira-Santos, Luciana C. Gomes, Rita Vieira, Jelmer Sjollema, Olívia S. G. P. Soares and Filipe J. Mergulhão
Coatings 2023, 13(8), 1324; https://doi.org/10.3390/coatings13081324 - 28 Jul 2023
Cited by 3 | Viewed by 1851
Abstract
Graphene and its functionalized derivatives have been increasingly applied in the biomedical field, particularly in the production of antimicrobial and anti-adhesive surfaces. This study aimed to evaluate the performance of graphene oxide (GO)/polydimethylsiloxane (PDMS) composites against Staphylococcus aureus and Pseudomonas aeruginosa biofilms. GO/PDMS [...] Read more.
Graphene and its functionalized derivatives have been increasingly applied in the biomedical field, particularly in the production of antimicrobial and anti-adhesive surfaces. This study aimed to evaluate the performance of graphene oxide (GO)/polydimethylsiloxane (PDMS) composites against Staphylococcus aureus and Pseudomonas aeruginosa biofilms. GO/PDMS composites containing different GO loadings (1, 3, and 5 wt.%) were synthesized and characterized regarding their morphology, roughness, and hydrophobicity, and tested for their ability to inhibit biofilm formation under conditions that mimic urinary tract environments. Biofilm formation was assessed by determining the number of total and culturable cells. Additionally, the antibacterial mechanisms of action of GO were investigated for the tested uropathogens. Results indicated that the surfaces containing GO had greater roughness and increased hydrophobicity than PDMS. Biofilm analysis showed that the 1 wt.% GO/PDMS composite was the most effective in reducing S. aureus biofilm formation. In opposition, P. aeruginosa biofilms were not inhibited by any of the synthesized composites. Furthermore, 1% (w/v) GO increased the membrane permeability, metabolic activity, and endogenous reactive oxygen species (ROS) synthesis in S. aureus. Altogether, these results suggest that GO/PDMS composites are promising materials for application in urinary catheters, although further investigation is required. Full article
(This article belongs to the Special Issue Advances in Antibacterial and Antivirus Materials and Coatings: From Fundamentals to Application)
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13 pages, 1788 KiB  
Article
N-Doped Carbon Nanoparticles as Antibacterial Agents on Escherichia coli: The Role of the Size and Chemical Composition of Nanoparticles
by David Lopez-Diaz, María Dolores Merchán, Pilar Pérez and María Mercedes Velázquez
Coatings 2023, 13(7), 1169; https://doi.org/10.3390/coatings13071169 - 28 Jun 2023
Cited by 2 | Viewed by 1529
Abstract
In the last years N-doped carbon nanoparticles have been shown to have improved antibacterial activity over the undoped nanomaterial, but it is difficult to find correlations between the structure of the nanoparticle and its antibacterial activity. This prevents us from proposing a clear [...] Read more.
In the last years N-doped carbon nanoparticles have been shown to have improved antibacterial activity over the undoped nanomaterial, but it is difficult to find correlations between the structure of the nanoparticle and its antibacterial activity. This prevents us from proposing a clear antibacterial mechanism and makes it difficult to select materials with the best physical and chemical properties for use as antibacterial agents. With this purpose, here, we analyze the effect of, the size and the surface chemical composition of four N-doped carbon nanoparticles on the growth of Escherichia coli bacteria, used in this work as a model of Gram-negative bacteria. Our results indicated great antibacterial activity as the concentration of the carbon nanoparticles increased. The IC50 values obtained ranged between 23 and 34 μg/mL, the lowest values found in the literature for CNPs in the absence of metals. The reduction rate was analyzed using a Ligand-Substrate model based on Monod’s equation, which allows us to interpret the dependence of the nanoparticle-bacteria affinity with the nanomaterial structure. The results of the model indicate the contribution of two mechanisms, oxidative stress and the nanoknife in the antibacterial process on Escherichia coli bacteria. Full article
(This article belongs to the Special Issue Advances in Antibacterial and Antivirus Materials and Coatings: From Fundamentals to Application)
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