Advanced Surface Engineering of Biocompatible Coatings: Innovation and Application

A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Surface Coatings for Biomedicine and Bioengineering".

Deadline for manuscript submissions: 15 January 2026 | Viewed by 544

Special Issue Editors


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Guest Editor
School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, China
Interests: surface modification of medical materials; biotribology; bioactivity; lubricating oil additives

E-Mail Website
Guest Editor
School of Chemical Engineering, Shanghai Institute of Technology, Shanghai 201418, China
Interests: Lubricant additives; tribology; friction; wear; lubricating grease; lubrication; surface and interface
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Special Issue Information

Dear colleagues,

Theoretical and experimental research on the surface engineering of new functional biomaterials represents one of the most advanced and promising research directions in biomaterials science and engineering. As the global population ages and sports injuries become more common, the incidence of orthopedic diseases has significantly increased, which has directly driven the rapid growth of the orthopedic implant market. As an essential means to improve patient quality of life, the performance of orthopedic implants is directly linked to treatment outcomes and patient rehabilitation processes. However, the success of implants depends not only on their primary materials but also on their surface properties, such as biocompatibility, antimicrobial characteristics, and mechanical strength, which are critical determinants of long-term efficacy. Moreover, the clinical advancement of non-implantable devices like oral patches and skin microneedles also hinges on the development of advanced biomaterials and surface engineering. Surface engineering techniques can significantly enhance the overall performance of implants by optimizing their interaction with the biological environment.

This Special Issue aims to provide a platform for academic exchange on the following research topics:

  1. Theoretical and experimental research progress on biomedical coatings in promoting bone integration, inhibiting inflammatory responses, and preventing infections.
  2. Development and application of novel bioactive functional materials (such as antibacterial coatings, drug release coatings, tissue patches, and biosignal response coatings).
  3. Biomedical functional coatings fabricated using advanced preparation techniques (such as 3D printing, plasma spraying, atomic layer deposition, and electrochemical deposition).
  4. High-performance biomedical coatings developed for extreme physiological environments (such as high stress, corrosive body fluids, and dynamic loads).
  5. Research on the degradation mechanisms of coatings in complex physiological environments, including biological corrosion, mechanical wear, and fatigue failure.
  6. Development of new methods for evaluating the performance of biomedical coatings, with a focus on the interaction of multiple factors, such as biological, chemical, and mechanical aspects, and the ability to predict long-term material performance.
  7. Use of computer simulation technology to predict the performance, durability, and reliability of coatings in physiological environments and establish a correlation model between experimental data and clinical performance.

We invite you to submit your contributions promoting the development of the field of biomedical coatings. We look forward to highlighting innovative research that makes significant contributions to improving the performance and safety of medical implants.

Dr. Chenchen Wang
Dr. Jincan Yan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • wear-resistant and corrosion-resistant coatings
  • biomimetic coatings
  • surface modification of bone implants
  • fretting wear at bone interfaces
  • biological lubricating materials

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Published Papers (1 paper)

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Research

20 pages, 5547 KiB  
Article
Multi-Modal Mechanical Response of Self-Healing Double-Network Hydrogel Coatings Based on Schiff Base Bond
by Yanan Li, Wenbin Hu, Qike Gao, Jincan Yan, Guan Wang, Sheng Han, Chenchen Wang and Xiaozheng Hou
Coatings 2025, 15(5), 552; https://doi.org/10.3390/coatings15050552 - 5 May 2025
Viewed by 417
Abstract
Ti6Al4V alloy is one of the most widely used orthopedic implants due to its low density, high strength and good biocompatibility, but surface tribology limits its service life and performance. In this paper, a layer of dynamic double-network hydrogel based on a Schiff [...] Read more.
Ti6Al4V alloy is one of the most widely used orthopedic implants due to its low density, high strength and good biocompatibility, but surface tribology limits its service life and performance. In this paper, a layer of dynamic double-network hydrogel based on a Schiff base bond and a hydrogen bond was grafted on the surface of Ti6Al4V alloy by the mussel chemical self-assembly method. The -NH2 of acrylamide (AM) and -CHO of vanillin (VA) formed Schiff base bonds to form the first layer of a cross-linked network, a large number of hydrogen bonds were formed between the -OH of vanillin and the -OH of sodium alginate (SA) to provide the second layer of the cross-linked network and the network was properly regulated by introducing core–shell polymer nanoparticles (PDCS). Dynamic self-healing bonds, Schiff base bonds and hydrogen bonds endow qPDCS/SA/VA/AM hydrogels with self-healing ability, and the network structure destroyed under high strain (250%) can be rebuilt under low strain (1%). In the second cycle, G’ and G can recover almost the same value. PDCS/SA/VA/AM hydrogel coating can achieve dynamic repair through reversible Schiff base bond dissociation–recombination during friction, while 1000ppmPDCS/SA/VA/AM hydrogel coating can achieve stable friction reduction and low wear under multiple loads. Under 0.5 N load, the average friction coefficient of 1000ppmPDCS/SA/VA/AM hydrogel coating is as low as 0.157, which is 67.74% lower than the uncoated Ti6Al4V surface under the same load. Under 2 N load, 1000ppmPDCS/SA/VA/AM hydrogel coating remains stable and low-friction, and the average coefficient of friction (ACOF) can reach 0.130, which is 59.27% lower than the uncoated Ti6Al4V surface under the same load. The design idea of the hydrogel network regulated by core–shell polymer nanoparticles (PDCS) to achieve low friction and low wear provides a new strategy for biolubricating materials. Full article
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