Cancer Genetics and Pharmacology: Advancing Precision Therapeutics
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Biochemistry, Molecular and Cellular Biology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 38
Special Issue Editor
Special Issue Information
Dear Colleagues,
Cancer genetics stands at the forefront of oncology research, elucidating the molecular dynamics behind cancer development and progression. Recent breakthroughs in genomic technologies, together with a growing database on genetic anomalies, have been crucial in advancing our understanding and treatment of cancer. Despite these strides, challenges like tumor heterogeneity, therapy resistance, and application of genetic discoveries into effective clinical practices continue to pose significant hurdles.
This Research Topic aims to enhance and broaden our understanding of cancer genetics with a focus on its integration with pharmacology. It seeks to spur innovations in drug development, refine therapeutic methods, and advance the implementation of precise, genetics-driven treatment models. By tackling critical issues such as drug resistance and using genetic markers for customized treatment, it endeavors to move the field toward a more cohesive and targeted approach to cancer therapy.
To address the complexities of this field, we invite contributions that explore, but are not limited to, the following themes:
- Genetic Mutations and Cancer: Key drivers and their role in targeted therapy.
- Genomic Technologies: Impact of advanced tools like NGS and CRISPR-Cas9.
- Tumor Heterogeneity: Influence on treatment strategies and disease outcomes.
- Biomarkers and Diagnostics: Importance in early detection and therapeutic accuracy.
- Targeted Therapies: Development and hurdles in interventions informed by genetics.
- Immunogenomics: Genetic factors affecting immune evasion and immunotherapy.
- Epigenetic Modifications: Potential targets and pharmaceutical interventions.
- Pharmacogenomics and Personalized Medicine: Customizing treatments based on genetic profiles.
- Translational Research: Bridging genetic discoveries with clinical practice.
- Future Directions: Emerging therapies and strategic innovations in precision medicine.
Through a comprehensive evaluation, this Research Topic will deepen our understanding of cancer genetics' foundation, paving the way for revolutionary advancements in cancer treatment.
Dr. Baoming Wang
Guest Editor
Manuscript Submission Information
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Keywords
- cancer genetics
- epigenetic modifications
- pharmacogenomics
- personalized medicine
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