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Molecular Biology of Plant Genomics and Genetics

A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Plant Sciences".

Deadline for manuscript submissions: closed (31 December 2024) | Viewed by 2844

Special Issue Editor


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Guest Editor
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
Interests: bioinformatics; gene expression; gene regulation; molecular biology; plant physiology

Special Issue Information

Dear Colleagues,

The relationship between genotype and phenotype is essential in precision breeding. Therefore, it is crucial to understand how the genome regulates plant development, growth, and environmental adaptation, with a particular focus on the epigenetic mechanisms that shape agronomic traits.

Advancements in high-throughput sequencing technology have revolutionized plant research, making genomics, transcriptomics, proteomics, and metabolomics central areas of study. Epigenomics has also emerged as a key field, elucidating the changes in gene activity and expression that are regulated by epigenetic modifications, such as DNA methylation and histone modification. These insights are vital to our understanding of complex plant traits.

The integration of multi-omics data provides a comprehensive foundation for studying plant genome structure and function, gene localization, and genetic improvement. Bioinformatics and its associated databases play a crucial role in maximizing the potential of genomic resources.

This Special Issue aims to showcase cutting-edge applications in plant research, leveraging advanced technologies, such as molecular biology, gene editing, and multi-omics. We welcome all types of submissions within this dynamic field.

Dr. Sunita Kumari
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • plant genomics
  • transcriptomics
  • multi-omics
  • bioinformatics
  • genetic improvement

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Published Papers (1 paper)

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Review

38 pages, 11513 KiB  
Review
Use of CRISPR Technology in Gene Editing for Tolerance to Biotic Factors in Plants: A Systematic Review
by Marcelly Santana Mascarenhas, Fernanda dos Santos Nascimento, Anelita de Jesus Rocha, Mileide dos Santos Ferreira, Wanderley Diaciso dos Santos Oliveira, Lucymeire Souza Morais Lino, Tiago Antônio de Oliveira Mendes, Claudia Fortes Ferreira, Janay Almeida dos Santos-Serejo and Edson Perito Amorim
Curr. Issues Mol. Biol. 2024, 46(10), 11086-11123; https://doi.org/10.3390/cimb46100659 - 2 Oct 2024
Viewed by 2505
Abstract
The objective of this systematic review (SR) was to select studies on the use of gene editing by CRISPR technology related to plant resistance to biotic stresses. We sought to evaluate articles deposited in six electronic databases, using pre-defined inclusion and exclusion criteria. [...] Read more.
The objective of this systematic review (SR) was to select studies on the use of gene editing by CRISPR technology related to plant resistance to biotic stresses. We sought to evaluate articles deposited in six electronic databases, using pre-defined inclusion and exclusion criteria. This SR demonstrates that countries such as China and the United States of America stand out in studies with CRISPR/Cas. Among the most studied crops are rice, tomatoes and the model plant Arabidopsis thaliana. The most cited biotic agents include the genera, Xanthomonas, Manaporthe, Pseudomonas and Phytophthora. This SR also identifies several CRISPR/Cas-edited genes and demonstrates that plant responses to stressors are mediated by many complex signaling pathways. The Cas9 enzyme is used in most articles and Cas12 and 13 are used as additional editing tools. Furthermore, the quality of the articles included in this SR was validated by a risk of bias analysis. The information collected in this SR helps to understand the state of the art of CRISPR/Cas aimed at improving resistance to diseases and pests to understand the mechanisms involved in most host–pathogen relationships. This SR shows that the CRISPR/Cas system provides a straightforward method for rapid gene targeting, providing useful information for plant breeding programs. Full article
(This article belongs to the Special Issue Molecular Biology of Plant Genomics and Genetics)
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