Molecular Mechanisms of Gut Microbiota in Health, Immunity and Disease
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: closed (31 October 2025) | Viewed by 11938
Special Issue Editor
Interests: probiotics; bifidobacterium; bactobacillus; gut microbiome; CVD; diabetes; colitis; atherosclerosis; miRNA; drugs; antibiotic resistance; nutrients; metabolism; metabolites
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The complexity of the gut microbiome, which has far-reaching effects on all aspects of health, has made it a vital topic in research, enhancing our understanding of human physiology and pathology. Trillions of microorganisms, including bacteria, viruses, fungi, and archaea, make up the gut microbiome and communicate with the host using complex molecular mechanisms that affect multiple biological systems. Such interactions not only sustain digestive health but also modulate immune responses, affect metabolism, and interact with the central nervous system through the gut–brain axis. In this context, this Special Issue aims to explore this complex interplay further by deciphering the molecular crosstalk between gut microorganisms and the host. We aim to offer detailed insights into how the microbiota contribute to homeostasis, what goes wrong with dysbiosis, and how these changes correlate with either health benefits or disease states. By spotlighting the most recent advances in microbiota research, this Special Issue aims to expose the molecular bases by which microbiota are influencing immunity, inflammation, and chronic conditions, providing unprecedented insights into potential diagnostic and therapeutic strategies. Studies focused on broader areas of dietary-based therapeutic interventions, including prebiotics, probiotics, and targeting the microbiome, will be considered as well.
The human gut microbiota is a critical determinant of health and disease, functioning as a dynamic ecosystem that interacts intricately with its host. This Special Issue aims to provide a platform for cutting-edge research that explores the molecular mechanisms through which gut microbiota influence health, contribute to disease processes, and modulate immune responses. The scope of this Special Issue encompasses, but is not limited to, the following areas: gut microbiota and host health, microbiota in disease pathogenesis, immune system modulation by microbiota, microbiota-driven therapeutics, multi-omics and advanced methodologies, and environmental and lifestyle influences.
We invite submissions focusing on, but not limited to, the following topics:
- Gut microbiota and host health;
- Microbiota in disease pathogenesis;
- Immune system modulation by microbiota;
- Microbiota-driven therapeutic strategies;
- Multi-omics and advanced methodologies in microbiome research;
- Environmental and lifestyle influences on the microbiome.
By addressing these topics, this Special Issue aims to provide a comprehensive platform for cutting-edge research and foster advancements in our understanding of the gut microbiome’s molecular mechanisms.
Dr. Ahmad Ud Din
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- gut microbiome
- immune system
- probiotics
- prebiotics
- microbial metabolites
- microbiota–host interactions
- gut–brain axis
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
