Advances in Early Detection and Intervention in Children with Cerebral Palsy

Dear Colleagues,

Early diagnosis of cerebral palsy (CP) is crucial for initiating timely and targeted rehabilitative interventions. Current evidence indicates that brain magnetic resonance imaging (MRI), general movement (GM) assessment, and standardized neurological assessments such as the Hammersmith Infant Neurological Examination (HINE) are the most reliable predictors for CP diagnosis before five months of age.

However, in children younger than two years, establishing both the topography and functional prognosis of CP remains a challenge.

In addition to identifying the underlying functional architecture, a key component of early management lies in predicting developmental outcomes.

Early, individualized interventions have demonstrated efficacy in promoting neurodevelopment, improving motor performance, and strengthening family-centered care. Given the growing array of diagnostic and prognostic tools, the need for integrated clinical approaches is growing. These strategies go beyond a binary diagnostic perspective and place greater emphasis on the child's functional profile from the earliest stages of development. This Special Issue aims to bring together research on clinical tools and rehabilitation approaches that can be used to implement targeted rehabilitation interventions in children with CP.

We therefore trust in your valuable collaboration and look forward to receiving your contributions.

Dr. Matteo Porro
Dr. Odoardo Picciolini
Guest Editors

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