The Neurobiological Effects and Intergenerational Transmission of Early Life Trauma on Children and Adolescents
A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Neurology & Neurodevelopmental Disorders".
Deadline for manuscript submissions: closed (31 July 2021) | Viewed by 3907
Special Issue Editor
Special Issue Information
Dear Colleagues,
The effects of early life trauma on multiple neurobiological processes such as genetics, epigenetics, cellular, immune, endocrine, brain and metabolic function, neurocircuitry, and neurochemistry is well-established in the literature. However, the consequences and co-morbidities of these neurobiological changes are still being realized. There is now converging evidence to support the theory that offspring are affected by previous generations’ exposure to trauma. Intergenerational risk is transferred not only through the genome, DNA methylation, and histone modification, but also through chemical exchanges in the womb during critical phases of brain development and parental modelling after birth. Considering the current COVID-19 pandemic, the global implications regarding the long-term effects of prenatal stress and trauma, and intergenerational transmission of trauma, are extremely topical. Understanding the neurobiological changes associated with exposures to trauma is necessary for developing individualized and targeted interventions to prevent the long-term repercussions of trauma in both the individual and their future progeny. Understanding and promoting factors that contribute to resilience will be important for interrupting intergenerational transmissions of trauma.
The goal of this Special Issue in Children is to highlight recent advances in trauma research examining the impact of early life traumatic experiences on children and adolescents. Reviews and/or original research articles may be focused on the basic sciences, clinical research, or both. Research involving neurobiological changes associated with early life trauma, comorbidities, intergenerational transmission, social transmission, interventions, and resiliency factors are welcomed. It is the hope that the articles submitted to this Special Issue will help to bring the field one step closer to finding solutions to the intergenerational impact of trauma.
I look forward to receiving your contributions.
Dr. Jillian Vinall Miller
Guest Editor
Manuscript Submission Information
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Keywords
- trauma
- posttraumatic stress symptoms
- posttraumatic stress disorder
- adverse early childhood experiences
- neurobiology
- brain
- stress
- neuroimaging
- genetics
- epigenetics
- hormones
- neurotransmitters
- intergenerational transmission
- parent
- pregnancy
- pandemic
- COVID-19
- coronavirus
- child
- adolescent
- youth
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