Insulin-Dependent Diabetes Mellitus in Children and Adolescents: Challenges and Management
A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Global Pediatric Health".
Deadline for manuscript submissions: 15 February 2026 | Viewed by 40
Special Issue Editors
Interests: vitamin D; type 1 diabetes prevention; monogenic diabetes; Wolfram syndrome
Special Issues, Collections and Topics in MDPI journals
Interests: neonatal and infant infections; vaccine-preventable diseases; nutrition and growth; neonatal and pediatric intensive care
Interests: diabetes; blood glucose; diabetes mellitus; metabolism; metabolic diseases; glucose measurement; clinical endocrinology; lipid metabolism
Interests: insulin resistance; diabetes; glucose metabolism; metabolism; metabolic diseases; lipid metabolism; nutrition; hypertension; atherosclerosis; nutritional and metabolic diseases
Special Issue Information
Dear Colleagues,
We are pleased to announce a new Special Issue of Children (MDPI) entitled “Insulin-Dependent Diabetes Mellitus in Children and Adolescents: Challenges and Management.” This Special Issue aims to address the evolving landscape of insulin-dependent diabetes mellitus (IDDM), with a particular focus on the early differentiation of type 1 diabetes from other forms of monogenic or syndromic diabetes, effective prevention strategies, and innovations in treatment algorithms. Recent research emphasizes the need to refine diagnostic accuracy and expand multidisciplinary care frameworks. We welcome original research articles, case reports, clinical trials, and high-quality reviews addressing, but not limited to, the following topics:
- Primary and secondary prevention of Type 1 Diabetes—immunological, genetic, or environmental strategies.
- Timely diagnosis of neonatal and monogenic diabetes, including all MODY subtypes and Wolfram syndrome.
- Clinical algorithms for emergency management of diabetic ketoacidosis (DKA).
- Personalized algorithms for intensified insulin therapy protocols.
- New-generation insulin analogs and real-world outcomes.
- The role of ophthalmological evaluation at diagnosis and follow-up.
- Screening for and management of co-existing autoimmune diseases.
- Prevention and treatment of non-autoimmune metabolic comorbidities.
- Development of multidisciplinary treatment networks (ophthalmology, cardiology, psychiatry, neurology, and clinical genetics).
- Emerging disease-modifying treatments for syndromic diabetes (e.g., Wolfram syndrome)
Our goal is to compile a comprehensive volume that advances diagnostic and therapeutic standards in pediatric diabetes, bridges the gap between guidelines and real-world practice, and promotes international collaboration in research and care. In this Special Issue, we invite you to share your expertise as well as the results of your research with a variety of article types (original research manuscripts, reviews and case reports) addressing the above challenges.
Assoc. Prof. Dr. Dimitris T. Papadimitriou
Prof. Dr. Ioanna N. Grivea
Prof. Dr. Alexandra Bargiota
Prof. Dr. Vaia Lambadiari
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- type 1 diabetes prevention
- monogenic diabetes
- diabetic ketoacidosis
- novel treatments
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