Clinical Research and Recent Advances in Paediatric Allergic Diseases

Paediatric allergic diseases encompass a group of conditions including food allergy, eczema, asthma, and rhinoconjunctivitis. Individually, these illnesses cause children and their families to experience significant distress and disruption to their daily lives; this is magnified when the allergic march results in children developing more than one allergic disease. Although the symptoms of eczema, asthma, and rhinoconjunctivitis may be controlled with medication and food allergy managed with avoidance of the relevant allergen, there is currently no cure for these conditions. Whilst some children outgrow paediatric allergic diseases, many do not, and hence the allergic burden continues into adulthood, with resultant physical, psychosocial, and economic impacts on individuals and society.

Food allergy prevention trials show that the introduction of peanut protein in infancy prevents peanut allergy in a high-risk population and the introduction of egg before 6 months of age is likely to be beneficial in preventing egg allergy in the general population. Trials of food desensitization also show promise in increasing the threshold of reaction, providing some reassurance to families that accidental exposure to an allergen via cross contamination is unlikely to cause a severe reaction. Trials of immune-modulating treatments for asthma and eczema have resulted in improvements in the treatment of children with severe disease. Despite these recent advances, there are still many unanswered questions regarding the best way to prevent paediatric allergic disease, halt the atopic march, treat those who have these conditions, and reduce the burden of allergic disease on children, their families, and society. We welcome manuscripts that address any of these issues.

Dr. Helen Fisher
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.