Plasma Membrane Dynamics and Signaling

Dear Colleagues,

The easiest way to characterize programmed cell death is probably by the dynamic changes of the plasma membrane—lytic cell death and non-lytic cell death (apoptosis). Lytic cell death can be mediated by molecules such as MLKL (necroptosis) or gasdermin family proteins (pyroptosis). Lipid oxidation can also lead to plasma membrane lysis (ferroptosis). At the same time, repair mechanisms such as ESCRT machinery can counterbalance the loss of plasma membrane integrity. All these mechanisms together shape a unique consequence to each distinct form of cell death. Besides plasma membrane integrity change, the translocation of lipid components such as phosphatidylserine also contributes to defining the physiological outcomes of programmed cell death.

This Special Issue aims to summarize the current knowledge on programmed cell death and its biological consequences, which are usually determined/modulated by plasma membrane dynamics.

Dr. Yi-Nan Gong
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• programmed cell death
• apoptosis
• necroptosis
• pyroptosis
• ferroptosis
• plasma membrane integrity loss
• plasma membrane repair
• pore-forming
• phosphatidylserine