Cellular and Molecular Research of Plant-Derived Exosomes
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Plant, Algae and Fungi Cell Biology".
Deadline for manuscript submissions: 20 July 2026 | Viewed by 28
Special Issue Editor
Interests: plant exosomes; nano-vesicles; gut permeabiity; extra-cellular vesicles; cancer; microbiota; gut microbiome; gut microbiota; gut inglammation; colitis; neural ischemia; ischemic stroke; polycystic ovary syndrome; chemotherapy; miRNA
Special Issue Information
Dear Colleagues,
Emerging evidence positions plant-derived exosomes as sophisticated information carriers in intercellular and cross-kingdom communication, rapidly emerging as a transformative area in a translational research with significant therapeutic promise. These nanoscale vesicles transport a defined molecular signature—including proteins, lipids, and notably, small regulatory RNAs—from donor to recipient cells, directly influencing cellular fate and function. The central biological question driving current research is how plant cells assemble these complex cargoes and how the delivered molecules mechanistically reprogram target cells.
Key molecular investigations focus on the specificity of cargo sorting within the plant endosomal system and the stability of RNA cargo during vesicle transit. At the cellular interface, studies reveal that plant-derived exosome uptake triggers specific signal transduction pathways, leading to measurable outcomes such as altered gene expression profiles and modulated immune responses in recipient cells. The precise molecular interplay between vesicle surface components and host cell receptors is a critical area of active inquiry.
Thus, research on plant-derived exosomes extends beyond descriptive cataloguing to probing fundamental mechanisms of vesicle-based communication. Unravelling these processes provides a novel paradigm for understanding how biological information is packaged, transmitted, and decoded across cellular boundaries, offering profound insights into both plant cell biology and the principles of extracellular vesicle function in eukaryotic systems.
Dr. Mukesh Kumar Sriwastva
Guest Editor
Manuscript Submission Information
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Keywords
- plant-derived exosomes
- extracellular vesicles
- exosome isolation and characterization
- cross-kingdom communication
- therapeutic applications
- biomolecule cargo (proteins, RNAs, lipids)
- plant exosome-like nanoparticles
- drug delivery systems
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