Pathogenesis of Alcohol-Associated Hepatitis and Its Therapies
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 27 February 2026 | Viewed by 123
Special Issue Editor
Special Issue Information
Dear Colleagues,
Alcohol-associated liver disease (ALD) is a significant health burden that continues to increase in incidence. Basic and clinical research concerning the underlying mechanisms of liver injury in ALD has added to our understanding of the pathophysiology associated with liver injury and failure in that same span. Key factors like maladaptive inflammation, metabolic perturbations, co-morbidities, and genetic variations have all been implicated, and can drive reversible alcohol-related steatosis and steatohepatitis to more acutely severe and irreversible stages of ALD, like alcohol-associated hepatitis (AH). Despite many advances in our understanding of AH, they have yet to translate into meaningful improvements in patient outcomes.
We invite you to submit contributions highlighting the latest State-of-the-Art studies detailing the pathogenesis of AH, the preclinical development of novel targeted therapeutics, and in silico and in vivo innovations in disease modeling to this Special Issue.
Dr. Kyle Lauren Poulsen
Guest Editor
Manuscript Submission Information
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Keywords
- alcohol-associated hepatitis
- drug screening
- drug delivery
- pathophysiology
- therapeutics
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