Announcements

"Hypoxia-Inducible Factor-1α: The Master Regulator of Endothelial Cell Senescence in Vascular Aging"
by Matilde Alique, Elsa Sánchez-López, Guillermo Bodega, Chiara Giannarelli, Julia Carracedo and Rafael Ramírez
Cells 2020, 9(1), 195; https://doi.org/10.3390/cells9010195
Available online: https://www.mdpi.com/2073-4409/9/1/195

"Towards Age-Related Anti-Inflammatory Therapy: Klotho Suppresses Activation of ER and Golgi Stress Response in Senescent Monocytes"
by Jennifer Mytych, Przemysław Sołek, Agnieszka Będzińska, Kinga Rusinek, Aleksandra Warzybok, Anna Tabęcka-Łonczyńska and Marek Koziorowski
Cells 2020, 9(2), 261; https://doi.org/10.3390/cells9020261
Available online: https://www.mdpi.com/2073-4409/9/2/261

"Beyond Tumor Suppression: Senescence in Cancer Stemness and Tumor Dormancy"
by Francisco Triana-Martínez, María Isabel Loza and Eduardo Domínguez
Cells 2020, 9(2), 346; https://doi.org/10.3390/cells9020346
Available online: https://www.mdpi.com/2073-4409/9/2/346

"Granulins Regulate Aging Kinetics in the Adult Zebrafish Telencephalon"
by Alessandro Zambusi, Özge Pelin Burhan, Rossella Di Giaimo, Bettina Schmid and Jovica Ninkovic
Cells 2020, 9(2), 350; https://doi.org/10.3390/cells9020350
Available online: https://www.mdpi.com/2073-4409/9/2/350

"Structural Features of Nucleoprotein CST/Shelterin Complex Involved in the Telomere Maintenance and Its Association with Disease Mutations"
by Mohd. Amir, Parvez Khan, Aarfa Queen, Ravins Dohare, Mohamed F. Alajmi, Afzal Hussain, Asimul Islam, Faizan Ahmad and Md. Imtaiyaz Hassan
Cells 2020, 9(2), 359; https://doi.org/10.3390/cells9020359
Available online: https://www.mdpi.com/2073-4409/9/2/359

"The Histone Code of Senescence"
by Harikrishnareddy Paluvai, Eros Di Giorgio and Claudio Brancolini
Cells 2020, 9(2), 466; https://doi.org/10.3390/cells9020466
Available online: https://www.mdpi.com/2073-4409/9/2/466

"3,4-Dihydroxybenzalacetone (DBL) Prevents Aging-Induced Myocardial Changes in Senescence-Accelerated Mouse-Prone 8 (SAMP8) Mice"
by Vijayasree V. Giridharan, Vengadeshprabhu Karupppagounder, Somasundaram Arumugam, Yutaka Nakamura, Ashrith Guha, Tatiana Barichello, Joao Quevedo, Kenichi Watanabe, Tetsuya Konishi and Rajarajan A. Thandavarayan
Cells 2020, 9(3), 597; https://doi.org/10.3390/cells9030597
Available online: https://www.mdpi.com/2073-4409/9/3/597

"The Immune Response Against Human Cytomegalovirus Links Cellular to Systemic Senescence"
by John J. Heath and Michael D. Grant
Cells 2020, 9(3), 766; https://doi.org/10.3390/cells9030766
Available online: https://www.mdpi.com/2073-4409/9/3/766

"SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction"
by Jennifer Gorwood, Tina Ejlalmanesh, Christine Bourgeois, Matthieu Mantecon, Cindy Rose, Michael Atlan, Delphine Desjardins, Roger Le Grand, Véronique Béréziat, Olivier Lambotte et al.
Cells 2020, 9(4), 854; https://doi.org/10.3390/cells9040854
Available online: https://www.mdpi.com/2073-4409/9/4/854

"New Insights from IGF-IR Stimulating Activity Analyses: Pathological Considerations"
by Joseph A.M.J.L. Janssen
Cells 2020, 9(4), 862; https://doi.org/10.3390/cells9040862
Available online: https://www.mdpi.com/2073-4409/9/4/862

"Exploring the Relevance of Senotherapeutics for the Current SARS-CoV-2 Emergency and Similar Future Global Health Threats"
by Marco Malavolta, Robertina Giacconi, Dario Brunetti, Mauro Provinciali and Fabrizio Maggi
Cells 2020, 9(4), 909; https://doi.org/10.3390/cells9040909
Available online: https://www.mdpi.com/2073-4409/9/4/909

"Insights from In Vivo Studies of Cellular Senescence"
by Luis I. Prieto, Sara I. Graves and Darren J. Baker
Cells 2020, 9(4), 954; https://doi.org/10.3390/cells9040954
Available online: https://www.mdpi.com/2073-4409/9/4/954

"Nicotine in Senescence and Atherosclerosis"
by Ann Marie Centner, Pradeep G. Bhide and Gloria Salazar
Cells 2020, 9(4), 1035; https://doi.org/10.3390/cells9041035
Available online: https://www.mdpi.com/2073-4409/9/4/1035

"Targeting the IGF-Axis for Cancer Therapy: Development and Validation of an IGF-Trap as a Potential Drug"
by Yinhsuan Michely Chen, Shu Qi, Stephanie Perrino, Masakazu Hashimoto and Pnina Brodt
Cells 2020, 9(5), 1098; https://doi.org/10.3390/cells9051098
Available online: https://www.mdpi.com/2073-4409/9/5/1098

"Alpha-Synuclein and LRRK2 in Synaptic Autophagy: Linking Early Dysfunction to Late-Stage Pathology in Parkinson’s Disease"
by Giulia Lamonaca and Mattia Volta
Cells 2020, 9(5), 1115; https://doi.org/10.3390/cells9051115
Available online: https://www.mdpi.com/2073-4409/9/5/1115

"IGFBP-3/IGFBP-3 Receptor System as an Anti-Tumor and Anti-Metastatic Signaling in Cancer"
by Qing Cai, Mikhail Dozmorov and Youngman Oh
Cells 2020, 9(5), 1261; https://doi.org/10.3390/cells9051261
Available online: https://www.mdpi.com/2073-4409/9/5/1261

"Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation"
by Ellen E. Salmon, Jason J. Breithaupt and George A. Truskey
Cells 2020, 9(5), 1292; https://doi.org/10.3390/cells9051292
Available online: https://www.mdpi.com/2073-4409/9/5/1292

"Insulin-like Growth Factor-1 and IGF Binding Proteins Predict All-Cause Mortality and Morbidity in Older Adults"
by William B. Zhang, Sandra Aleksic, Tina Gao, Erica F. Weiss, Eleni Demetriou, Joe Verghese, Roee Holtzer, Nir Barzilai and Sofiya Milman
Cells 2020, 9(6), 1368; https://doi.org/10.3390/cells9061368
Available online: https://www.mdpi.com/2073-4409/9/6/1368

"Effects of GH/IGF on the Aging Mitochondria"
by Sher Bahadur Poudel, Manisha Dixit, Maria Neginskaya, Karthik Nagaraj, Evgeny Pavlov, Haim Werner and Shoshana Yakar
Cells 2020, 9(6), 1384; https://doi.org/10.3390/cells9061384
Available online: https://www.mdpi.com/2073-4409/9/6/1384

"Experimental Models of Sarcopenia: Bridging Molecular Mechanism and Therapeutic Strategy"
by Sakulrat Mankhong, Sujin Kim, Sohee Moon, Hyo-Bum Kwak, Dong-Ho Park and Ju-Hee Kang
Cells 2020, 9(6), 1385; https://doi.org/10.3390/cells9061385
Available online: https://www.mdpi.com/2073-4409/9/6/1385

"Targeting Cardiac Stem Cell Senescence to Treat Cardiac Aging and Disease"
by Eleonora Cianflone, Michele Torella, Flavia Biamonte, Antonella De Angelis, Konrad Urbanek, Francesco S. Costanzo, Marcello Rota, Georgina M. Ellison-Hughes and Daniele Torella
Cells 2020, 9(6), 1558; https://doi.org/10.3390/cells9061558
Available online: https://www.mdpi.com/2073-4409/9/6/1558

"DNA Damage- But Not Enzalutamide-Induced Senescence in Prostate Cancer Promotes Senolytic Bcl-xL Inhibitor Sensitivity"
by Nicolas Malaquin, Arthur Vancayseele, Sophie Gilbert, Laureen Antenor-Habazac, Marc-Alexandre Olivier, Zakia Ait Ali Brahem, Fred Saad, Guila Delouya and Francis Rodier
Cells 2020, 9(7), 1593; https://doi.org/10.3390/cells9071593
Available online: https://www.mdpi.com/2073-4409/9/7/1593

"Peroxisome Proliferator-Activated Receptors and Caloric Restriction—Common Pathways Affecting Metabolism, Health, and Longevity"
by Kalina Duszka, András Gregor, Hervé Guillou, Jürgen König and Walter Wahli
Cells 2020, 9(7), 1708; https://doi.org/10.3390/cells9071708
Available online: https://www.mdpi.com/2073-4409/9/7/1708

"Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations"
by Pilar Rivero-Ríos, Maria Romo-Lozano, Belén Fernández, Elena Fdez and Sabine Hilfiker
Cells 2020, 9(7), 1719; https://doi.org/10.3390/cells9071719
Available online: https://www.mdpi.com/2073-4409/9/7/1719

"Implications of Insulin-Like Growth Factor-1 in Skeletal Muscle and Various Diseases"
by Syed Sayeed Ahmad, Khurshid Ahmad, Eun Ju Lee, Yong-Ho Lee and Inho Choi
Cells 2020, 9(8), 1773; https://doi.org/10.3390/cells9081773
Available online: https://www.mdpi.com/2073-4409/9/8/1773

"Glucose-Regulated Protein 94 (GRP94): A Novel Regulator of Insulin-Like Growth Factor Production"
by Yair Argon, Sophie E. Bresson, Michal T. Marzec and Adda Grimberg
Cells 2020, 9(8), 1844; https://doi.org/10.3390/cells9081844
Available online: https://www.mdpi.com/2073-4409/9/8/1844

"Robustness during Aging—Molecular Biological and Physiological Aspects"
by Emanuel Barth, Patricia Sieber, Heiko Stark and Stefan Schuster
Cells 2020, 9(8), 1862; https://doi.org/10.3390/cells9081862
Available online: https://www.mdpi.com/2073-4409/9/8/1862

"Mechanisms of IGF-1-Mediated Regulation of Skeletal Muscle Hypertrophy and Atrophy"
by Tadashi Yoshida and Patrice Delafontaine
Cells 2020, 9(9), 1970; https://doi.org/10.3390/cells9091970
Available online: https://www.mdpi.com/2073-4409/9/9/1970

"The MAO Inhibitor Tranylcypromine Alters LPS- and Aβ-Mediated Neuroinflammatory Responses in Wild-type Mice and a Mouse Model of AD"
by HyunHee Park, Kyung-Min Han, Hyongjun Jeon, Ji-Soo Lee, Hyunju Lee, Seong Gak Jeon, Jin-Hee Park, Yu Gyung Kim, Yuxi Lin, Young-Ho Leel et al.
Cells 2020, 9(9), 1982; https://doi.org/10.3390/cells9091982
Available online: https://www.mdpi.com/2073-4409/9/9/1982

"Senescence Induction by Combined Ionizing Radiation and DNA Damage Response Inhibitors in Head and Neck Squamous Cell Carcinoma Cells"
by Clara Dobler, Tina Jost, Markus Hecht, Rainer Fietkau and Luitpold Distel
Cells 2020, 9(9), 2012; https://doi.org/10.3390/cells9092012
Available online: https://www.mdpi.com/2073-4409/9/9/2012

"Raloxifene and n-Acetylcysteine Ameliorate TGF-Signalling in Fibroblasts from Patients with Recessive Dominant Epidermolysis Bullosa"
by Tania Aguado, Marta García, Adela García, Gemma Ferrer-Mayorga, Lucía Martínez-Santamaría, Marcela del Río, Luisa-María Botella and José-María Sánchez-Puelles
Cells 2020, 9(9), 2108; https://doi.org/10.3390/cells9092108
Available online: https://www.mdpi.com/2073-4409/9/9/2108

"Cell Senescence, Multiple Organelle Dysfunction and Atherosclerosis"
by Gisela Machado-Oliveira, Cristiano Ramos, André R. A. Marques and Otília V. Vieira
Cells 2020, 9(10), 2146; https://doi.org/10.3390/cells9102146
Available online: https://www.mdpi.com/2073-4409/9/10/2146

"The Multimodal Serotonergic Agent Vilazodone Inhibits L-DOPA-Induced Gene Regulation in Striatal Projection Neurons and Associated Dyskinesia in an Animal Model of Parkinson’s Disease"
by Feras Altwal, Connor Moon, Anthony R. West and Heinz Steiner
Cells 2020, 9(10), 2265; https://doi.org/10.3390/cells9102265
Available online: https://www.mdpi.com/2073-4409/9/10/2265

"Understanding IGF-II Action through Insights into Receptor Binding and Activation"
by Andrew J. Blyth, Nicholas S. Kirk and Briony E. Forbes
Cells 2020, 9(10), 2276; https://doi.org/10.3390/cells9102276
Available online: https://www.mdpi.com/2073-4409/9/10/2276

"Exercise as a Therapeutic Strategy for Sarcopenia in Heart Failure: Insights into Underlying Mechanisms"
by Jinkyung Cho, Youngju Choi, Pavol Sajgalik, Mi-Hyun No, Sang-Hyun Lee, Sujin Kim, Jun-Won Heo, Eun-Jeong Cho, Eunwook Chang, Ju-Hee Kangl et al.
Cells 2020, 9(10), 2284; https://doi.org/10.3390/cells9102284
Available online: https://www.mdpi.com/2073-4409/9/10/2284

"Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues"
by Lucia Iannotta, Alice Biosa, Jillian H. Kluss, Giulia Tombesi, Alice Kaganovich, Susanna Cogo, Nicoletta Plotegher, Laura Civiero, Evy Lobbestael, Veerle Baekelandtl.
Cells 2020, 9(11), 2344; https://doi.org/10.3390/cells9112344
Available online: https://www.mdpi.com/2073-4409/9/11/2344

"Cellular Senescence in Renal and Urinary Tract Disorders"
by Yohan Santin, Philippe Lluel, Pascal Rischmann, Xavier Gamé, Jeanne Mialet-Perez and Angelo Parini Björn H. Falkenburger
Cells 2020, 9(11), 2420; https://doi.org/10.3390/cells9112420
Available online: https://www.mdpi.com/2073-4409/9/11/2420

"Changes in Striatal Medium Spiny Neuron Morphology Resulting from Dopamine Depletion Are Reversible"
by Victoria Sofie Witzig, Daniel Komnig and Björn H. Falkenburger
Cells 2020, 9(11), 2441; https://doi.org/10.3390/cells9112441
Available online: https://www.mdpi.com/2073-4409/9/11/2441

"The Endoplasmic Reticulum Stress/Unfolded Protein Response and Their Contributions to Parkinson’s Disease Physiopathology"
by Cristine Alves da Costa, Wejdane El Manaa, Eric Duplan and Frédéric Checler
Cells 2020, 9(11), 2495; https://doi.org/10.3390/cells9112495
Available online: https://www.mdpi.com/2073-4409/9/11/2495

"Proteomic Insights into Senescence of Testicular Peritubular Cells from a Nonhuman Primate Model"
by Jan B. Stöckl, Nina Schmid, Florian Flenkenthaler, Charis Drummer, Rüdiger Behr, Artur Mayerhofer, Georg J. Arnold and Thomas Fröhlich
Cells 2020, 9(11), 2498; https://doi.org/10.3390/cells9112498
Available online: https://www.mdpi.com/2073-4409/9/11/2498

"Molecular Mechanisms to Target Cellular Senescence in Hepatocellular Carcinoma"
by Constanze Mittermeier, Andreas Konopa and Susanne Muehlich
Cells 2020, 9(12), 2540; https://doi.org/10.3390/cells9122540
Available online: https://www.mdpi.com/2073-4409/9/12/2540

"Pathological Functions of LRRK2 in Parkinson’s Disease"
by Ga Ram Jeong and Byoung Dae Lee
Cells 2020, 9(12), 2565; https://doi.org/10.3390/cells9122565
Available online: https://www.mdpi.com/2073-4409/9/12/2565

"Nano-Based Theranostic Tools for the Detection and Elimination of Senescent Cells"
by Jagoda Adamczyk-Grochala and Anna Lewinska
Cells 2020, 9(12), 2659; https://doi.org/10.3390/cells9122659
Available online: https://www.mdpi.com/2073-4409/9/12/2659

"Identification of Targets from LRRK2 Rescue Phenotypes"
by Joanne Toh, Ling Ling Chua, Patrick Ho, Edwin Sandanaraj, Carol Tang, Hongyan Wang and Eng King Tan
Cells 2021, 10(1), 76; https://doi.org/10.3390/cells10010076
Available online: https://www.mdpi.com/2073-4409/10/1/76

"Seeding Propensity and Characteristics of Pathogenic αSyn Assemblies in Formalin-Fixed Human Tissue from the Enteric Nervous System, Olfactory Bulb, and Brainstem in Cases Staged for Parkinson’s Disease"
by Alexis Fenyi, Charles Duyckaerts, Luc Bousset, Heiko Braak, Kelly Del Tredici, Ronald Melki and on behalf of the Brainbank Neuro-CEB Neuropathology Network
Cells 2021, 10(1), 139; https://doi.org/10.3390/cells10010139
Available online: https://www.mdpi.com/2073-4409/10/1/139

"Microglial Turnover in Ageing-Related Neurodegeneration: Therapeutic Avenue to Intervene in Disease Progression"
by Shofiul Azam, Md. Ezazul Haque, In-Su Kim and Dong-Kug Choi
Cells 2021, 10(1), 150; https://doi.org/10.3390/cells10010150
Available online: https://www.mdpi.com/2073-4409/10/1/150

"The Impact of HIV- and ART-Induced Mitochondrial Dysfunction in Cellular Senescence and Aging"
by Madison Schank, Juan Zhao, Jonathan P. Moorman and Zhi Q. Yao
Cells 2021, 10(1), 174; https://doi.org/10.3390/cells10010174
Available online: https://www.mdpi.com/2073-4409/10/1/174

"Lipoprotein Lipase Regulates Microglial Lipid Droplet Accumulation"
by Bailey A. Loving, Maoping Tang, Mikaela C. Neal, Sachi Gorkhali, Robert Murphy, Robert H. Eckel and Kimberley D. Bruce
Cells 2021, 10(2), 198; https://doi.org/10.3390/cells10020198
Available online: https://www.mdpi.com/2073-4409/10/2/198

"The Jekyll and Hyde of Cellular Senescence in Cancer"
by Dilara Demirci, Bengisu Dayanc, Fatma Aybuke Mazi and Serif Senturk
Cells 2021, 10(2), 208; https://doi.org/10.3390/cells10020208
Available online: https://www.mdpi.com/2073-4409/10/2/208

"Aging and Microglial Response following Systemic Stimulation with Escherichia coli in Mice"
by Inge C.M. Hoogland, Dunja Westhoff, Joo-Yeon Engelen-Lee, Mercedes Valls Seron, Judith H.M.P. Houben-Weerts, David J. van Westerloo, Tom van der Poll, Willem A. van Gool and Diederik van de Beek
Cells 2021, 10(2), 279; https://doi.org/10.3390/cells10020279
Available online: https://www.mdpi.com/2073-4409/10/2/279

"The Role of DJ-1 in Cellular Metabolism and Pathophysiological Implications for Parkinson’s Disease"
by Pauline Mencke, Ibrahim Boussaad, Chiara D. Romano, Toshimori Kitami, Carole L. Linster and Rejko Krüger
Cells 2021, 10(2), 347; https://doi.org/10.3390/cells10020347
Available online: https://www.mdpi.com/2073-4409/10/2/347

"PBK/TOPK: A Therapeutic Target Worthy of Attention"
by Ziping Han, Lingzhi Li, Yuyou Huang, Haiping Zhao and Yumin Luo
Cells 2021, 10(2), 371; https://doi.org/10.3390/cells10020371
Available online: https://www.mdpi.com/2073-4409/10/2/371

"Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies"
by Inês C. Brás and Tiago F. Outeiro
Cells 2021, 10(2), 375; https://doi.org/10.3390/cells10020375
Available online: https://www.mdpi.com/2073-4409/10/2/375

"Statins as a Therapeutic Approach for the Treatment of Pseudoxanthoma Elasticum Patients: Evaluation of the Spectrum Efficacy of Atorvastatin In Vitro"
by Janina Tiemann, Christopher Lindenkamp, Ricarda Plümers, Isabel Faust, Cornelius Knabbe and Doris Hendig
Cells 2021, 10(2), 442; https://doi.org/10.3390/cells10020442
Available online: https://www.mdpi.com/2073-4409/10/2/442

"Development of a Sensitive Bioassay for the Analysis of IGF-Related Activation of AKT/mTOR Signaling in Biological Matrices"
by Michael Walz, Christine Höflich, Christina Walz, Daniela Ohde, Julia Brenmoehl, Mandy Sawitzky, Andreas Vernunft, Uwe K. Zettl, Susanne Holtze, Thomas B. Hildebrandtl et al.
Cells 2021, 10(3), 482; https://doi.org/10.3390/cells10030482
Available online: https://www.mdpi.com/2073-4409/10/3/482

"Deficiency of Biogenic Amines Modulates the Activity of Hypoglossal Nerve in the Reserpine Model of Parkinson’s Disease"
by Monika Jampolska, Kryspin Andrzejewski, Małgorzata Zaremba, Ilona Joniec-Maciejak and Katarzyna Kaczyńska
Cells 2021, 10(3), 531; https://doi.org/10.3390/cells10030531
Available online: https://www.mdpi.com/2073-4409/10/3/531

"An Analysis of the Neurological and Molecular Alterations Underlying the Pathogenesis of Alzheimer’s Disease"
by Chantal Vidal and Li Zhang
Cells 2021, 10(3), 546; https://doi.org/10.3390/cells10030546
Available online: https://www.mdpi.com/2073-4409/10/3/546

"The Importance of Drosophila melanogaster Research to UnCover Cellular Pathways Underlying Parkinson’s Disease"
by Melissa Vos and Christine Klein
Cells 2021, 10(3), 579; https://doi.org/10.3390/cells10030579
Available online: https://www.mdpi.com/2073-4409/10/3/579

"Mural Cells: Potential Therapeutic Targets to Bridge Cardiovascular Disease and Neurodegeneration"
by Alexander Lin, Niridu Jude Peiris, Harkirat Dhaliwal, Maria Hakim, Weizhen Li, Subramaniam Ganesh, Yogambha Ramaswamy, Sanjay Patel and Ashish Misra
Cells 2021, 10(3), 593; https://doi.org/10.3390/cells10030593
Available online: https://www.mdpi.com/2073-4409/10/3/593

"Cytokine Profile in Plasma Extracellular Vesicles of Parkinson’s Disease and the Association with Cognitive Function"
by Lung Chan, Chen-Chih Chung, Jia-Hung Chen, Ruan-Ching Yu and Chien-Tai Hong
Cells 2021, 10(3), 604; https://doi.org/10.3390/cells10030604
Available online: https://www.mdpi.com/2073-4409/10/3/604

"Key Signaling Pathways in Aging and Potential Interventions for Healthy Aging"
by Mengdi Yu, Hongxia Zhang, Brian Wang, Yinuo Zhang, Xiaoying Zheng, Bei Shao, Qichuan Zhuge and Kunlin Jin
Cells 2021, 10(3), 660; https://doi.org/10.3390/cells10030660
Available online: https://www.mdpi.com/2073-4409/10/3/660

"A Mouse Model for Studying the Development of Apical Periodontitis with Age"
by Elisheva Goldman, Eli Reich, Bar Roshihotzki, Maya Saketkhou, Sharon Wald, Ayana Goldstein, Yehuda Klein, Itzhak Abramovitz and Michael Klutstein
Cells 2021, 10(3), 671; https://doi.org/10.3390/cells10030671
Available online: https://www.mdpi.com/2073-4409/10/3/671

"Role of Sox2 in Learning, Memory, and Postoperative Cognitive Dysfunction in Mice"
by Lingli Gui, Zhen Luo, Weiran Shan and Zhiyi Zuo
Cells 2021, 10(4), 727; https://doi.org/10.3390/cells10040727
Available online: https://www.mdpi.com/2073-4409/10/4/727

"Chronic–Progressive Dopaminergic Deficiency Does Not Induce Midbrain Neurogenesis"
by Mareike Fauser, Francisco Pan-Montojo, Christian Richter, Philipp J. Kahle, Sigrid C. Schwarz, Johannes Schwarz, Alexander Storch and Andreas Hermann
Cells 2021, 10(4), 775; https://doi.org/10.3390/cells10040775
Available online: https://www.mdpi.com/2073-4409/10/4/775

"Sir4 Deficiency Reverses Cell Senescence by Sub-Telomere Recombination"
by Jun Liu, Xiaojing Hong, Lihui Wang, Chao-Ya Liang and Jun-Ping Liu
Cells 2021, 10(4), 778; https://doi.org/10.3390/cells10040778
Available online: https://www.mdpi.com/2073-4409/10/4/778

"Acute Ischemic Stroke at High Altitudes in China: Early Onset and Severe Manifestations"
by Moqi Liu, Mingzong Yan, Yong Guo, Zhankui Xie, Rui Li, Jialu Li, Changhong Ren, Xunming Ji and Xiuhai Guo
Cells 2021, 10(4), 809; https://doi.org/10.3390/cells10040809
Available online: https://www.mdpi.com/2073-4409/10/4/809

"Sirtuin 1 and Skin: Implications in Intrinsic and Extrinsic Aging—A Systematic Review"
by Angelika Bielach-Bazyluk, Edyta Zbroch, Hanna Mysliwiec, Alicja Rydzewska-Rosolowska, Katarzyna Kakareko, Iwona Flisiak and Tomasz Hryszko
Cells 2021, 10(4), 813; https://doi.org/10.3390/cells10040813
Available online: https://www.mdpi.com/2073-4409/10/4/813

"IL-1β Antibody Protects Brain from Neuropathology of Hypoperfusion"
by Dominic Quintana, Xuefang Ren, Heng Hu, Deborah Corbin, Elizabeth Engler-Chiurazzi, Muhammad Alvi and James Simpkins
Cells 2021, 10(4), 855; https://doi.org/10.3390/cells10040855
Available online: https://www.mdpi.com/2073-4409/10/4/855

"Advances in Understanding of the Role of Lipid Metabolism in Aging"
by Ki Wung Chung
Cells 2021, 10(4), 880; https://doi.org/10.3390/cells10040880
Available online: https://www.mdpi.com/2073-4409/10/4/880

"Treatment with Bacterial Biologics Promotes Healthy Aging and Traumatic Brain Injury Responses in Adult Drosophila, Modeling the Gut–Brain Axis and Inflammation Responses"
by Brandon Molina, Jessica Mastroianni, Ema Suarez, Brijinder Soni, Erica Forsberg and Kim Finley
Cells 2021, 10(4), 900; https://doi.org/10.3390/cells10040900
Available online: https://www.mdpi.com/2073-4409/10/4/900

"A Propagated Skeleton Approach to High Throughput Screening of Neurite Outgrowth for In Vitro Parkinson’s Disease Modelling"
by Justus Schikora, Nina Kiwatrowski, Nils Förster, Leonie Selbach, Friederike Ostendorf, Frida Pallapies, Britta Hasse, Judith Metzdorf, Ralf Gold, Axel Mosigl.
Cells 2021, 10(4), 931; https://doi.org/10.3390/cells10040931
Available online: https://www.mdpi.com/2073-4409/10/4/931

"Microglial Function and Regulation during Development, Homeostasis and Alzheimer’s Disease"
by Brad T. Casali and Erin G. Reed-Geaghan
Cells 2021, 10(4), 957; https://doi.org/10.3390/cells10040957
Available online: https://www.mdpi.com/2073-4409/10/4/957

"Mind the Gap: LRRK2 Phenotypes in the Clinic vs. in Patient Cells"
by Liesel Goveas, Eugénie Mutez, Marie-Christine Chartier-Harlin and Jean-Marc Taymans
Cells 2021, 10(5), 981; https://doi.org/10.3390/cells10050981
Available online: https://www.mdpi.com/2073-4409/10/5/981

"Abdominal Obesity-Related Disturbance of Insulin Sensitivity Is Associated with CD8⁺ EMRA Cells in the Elderly"
by Tim K. Boßlau, Paulina Wasserfurth, Britta Krüger, Thomas Reichel, Jana Palmowski, Josefine Nebl, Christopher Weyh, Alexander Schenk, Niklas Joisten, Frank Stahll.
Cells 2021, 10(5), 998; https://doi.org/10.3390/cells10050998
Available online: https://www.mdpi.com/2073-4409/10/5/998

"KLF5 Is Activated by Gene Amplification in Gastric Cancer and Is Essential for Gastric Cell Proliferation"
by Wei Chen, Jian Zhang, Huafeng Fu, Xun Hou, Qiao Su, Yulong He and Dongjie Yang
Cells 2021, 10(5), 1002; https://doi.org/10.3390/cells10051002
Available online: https://www.mdpi.com/2073-4409/10/5/1002

"Traumatic Brain Injury: Ultrastructural Features in Neuronal Ferroptosis, Glial Cell Activation and Polarization, and Blood–Brain Barrier Breakdown"
by Delong Qin, Junmin Wang, Anh Le, Tom J. Wang, Xuemei Chen and Jian Wang
Cells 2021, 10(5), 1009; https://doi.org/10.3390/cells10051009
Available online: https://www.mdpi.com/2073-4409/10/5/1009

"PEDF-Mediated Mitophagy Triggers the Visual Cycle by Enhancing Mitochondrial Functions in a H₂O₂-Injured Rat Model"
by Jae Yeon Kim, Sohae Park, Hee Jung Park, Se Ho Kim, Helen Lew and Gi Jin Kim
Cells 2021, 10(5), 1117; https://doi.org/10.3390/cells10051117
Available online: https://www.mdpi.com/2073-4409/10/5/1117

"Microglia in Aging and Alzheimer’s Disease: A Comparative Species Review"
by Melissa K. Edler, Isha Mhatre-Winters and Jason R. Richardson
Cells 2021, 10(5), 1138; https://doi.org/10.3390/cells10051138
Available online: https://www.mdpi.com/2073-4409/10/5/1138

"Molecular and Cellular Mechanisms Driving Cardiovascular Disease in Hutchinson-Gilford Progeria Syndrome: Lessons Learned from Animal Models"
by Ignacio Benedicto, Beatriz Dorado and Vicente Andrés
Cells 2021, 10(5), 1157; https://doi.org/10.3390/cells10051157
Available online: https://www.mdpi.com/2073-4409/10/5/1157

"Motor Cortex Stimulation Reversed Hypernociception, Increased Serotonin in Raphe Neurons, and Caused Inhibition of Spinal Astrocytes in a Parkinson’s Disease Rat Model"
by Ana Carolina P. Campos, Miriã B. Berzuíno, Gabriela R. Barbosa, Helena M. R. C. Freire, Patricia S. Lopes, Danielle V. Assis, Erich T. Fonoff and Rosana L. Pagano
Cells 2021, 10(5), 1158; https://doi.org/10.3390/cells10051158
Available online: https://www.mdpi.com/2073-4409/10/5/1158

"Berberine Improves Cognitive Impairment by Simultaneously Impacting Cerebral Blood Flow and β-Amyloid Accumulation in an APP/tau/PS1 Mouse Model of Alzheimer’s Disease"
by Chenghui Ye, Yubin Liang, Ying Chen, Yu Xiong, Yingfang She, Xiaochun Zhong, Hongda Chen and Min Huang
Cells 2021, 10(5), 1161; https://doi.org/10.3390/cells10051161
Available online: https://www.mdpi.com/2073-4409/10/5/1161

"Neuroinflammation: Integrated Nervous Tissue Response through Intercellular Interactions at the “Whole System” Scale"
by Daniele Nosi, Daniele Lana, Maria Grazia Giovannini, Giovanni Delfino and Sandra Zecchi-Orlandini
Cells 2021, 10(5), 1195; https://doi.org/10.3390/cells10051195
Available online: https://www.mdpi.com/2073-4409/10/5/1195

"The PI3K/Akt Pathway: Emerging Roles in Skin Homeostasis and a Group of Non-Malignant Skin Disorders"
by Yan Teng, Yibin Fan, Jingwen Ma, Wei Lu, Na Liu, Yingfang Chen, Weili Pan and Xiaohua Tao
Cells 2021, 10(5), 1219; https://doi.org/10.3390/cells10051219
Available online: https://www.mdpi.com/2073-4409/10/5/1219

"Milano—Torino Staging and Long-Term Survival in Chinese Patients with Amyotrophic Lateral Sclerosis"
by Ruojie He, Minying Zheng, Ling Lian and Xiaoli Yao
Cells 2021, 10(5), 1220; https://doi.org/10.3390/cells10051220
Available online: https://www.mdpi.com/2073-4409/10/5/1220

"Age-Related Alterations in the Testicular Proteome of a Non-Human Primate"
by Jan B. Stöckl, Nina Schmid, Florian Flenkenthaler, Charis Drummer, Rüdiger Behr, Artur Mayerhofer, Georg J. Arnold and Thomas Fröhlich
Cells 2021, 10(6), 1306; https://doi.org/10.3390/cells10061306
Available online: https://www.mdpi.com/2073-4409/10/6/1306

"Hallmarks of Aging in Macrophages: Consequences to Skin Inflammaging"
by Gabriela Rapozo Guimarães, Palloma Porto Almeida, Leandro de Oliveira Santos, Leane Perim Rodrigues, Juliana Lott de Carvalho and Mariana Boroni
Cells 2021, 10(6), 1323; https://doi.org/10.3390/cells10061323
Available online: https://www.mdpi.com/2073-4409/10/6/1323

"Utilizing Developmentally Essential Secreted Peptides Such as Thymosin Beta-4 to Remind the Adult Organs of Their Embryonic State—New Directions in Anti-Aging Regenerative Therapies"
by Klaudia Maar, Roland Hetenyi, Szabolcs Maar, Gabor Faskerti, Daniel Hanna, Balint Lippai, Aniko Takatsy and Ildiko Bock-Marquette
Cells 2021, 10(6), 1343; https://doi.org/10.3390/cells10061343
Available online: https://www.mdpi.com/2073-4409/10/6/1343

"The PINK1-Mediated Crosstalk between Neural Cells and the Underlying Link to Parkinson’s Disease"
by Elvira Pequeno Leites and Vanessa Alexandra Morais
Cells 2021, 10(6), 1395; https://doi.org/10.3390/cells10061395
Available online: https://www.mdpi.com/2073-4409/10/6/1395

"Effect of Rho-Associated Kinase Inhibitor and Mesenchymal Stem Cell-Derived Conditioned Medium on Corneal Endothelial Cell Senescence and Proliferation"
by Boyoung Jung, Hun Lee, Sumi Kim, Hungwon Tchah and Changmo Hwang
Cells 2021, 10(6), 1463; https://doi.org/10.3390/cells10061463
Available online: https://www.mdpi.com/2073-4409/10/6/1463

"The Olfactory Receptor Gene Product, OR5H2, Modulates Endometrial Cancer Cells Proliferation via Interaction with the IGF1 Signaling Pathway"
by Rand Shibel, Rive Sarfstein, Karthik Nagaraj, Lena Lapkina-Gendler, Zvi Laron, Manisha Dixit, Shoshana Yakar and Haim Werner
Cells 2021, 10(6), 1483; https://doi.org/10.3390/cells10061483
Available online: https://www.mdpi.com/2073-4409/10/6/1483

"The Impact of Obesity on Microglial Function: Immune, Metabolic and Endocrine Perspectives"
by Vasileia Ismini Alexaki
Cells 2021, 10(7), 1584; https://doi.org/10.3390/cells10071584
Available online: https://www.mdpi.com/2073-4409/10/7/1584

"Gene Expression Profile in Different Age Groups and Its Association with Cognitive Function in Healthy Malay Adults in Malaysia"
by Nur Fathiah Abdul Sani, Ahmad Imran Zaydi Amir Hamzah, Zulzikry Hafiz Abu Bakar, Yasmin Anum Mohd Yusof, Suzana Makpol, Wan Zurinah Wan Ngah and Hanafi Ahmad Damanhuri
Cells 2021, 10(7), 1611; https://doi.org/10.3390/cells10071611
Available online: https://www.mdpi.com/2073-4409/10/7/1611

"IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss"
by Adelaida M. Celaya, Lourdes Rodríguez-de la Rosa, Jose M. Bermúdez-Muñoz, José M. Zubeldia, Carlos Romá-Mateo, Carlos Avendaño, Federico V. Pallardó and Isabel Varela-Nieto
Cells 2021, 10(7), 1686; https://doi.org/10.3390/cells10071686
Available online: https://www.mdpi.com/2073-4409/10/7/1686

"Epigenetic Drifts during Long-Term Intestinal Organoid Culture"
by Torsten Thalheim, Susann Siebert, Marianne Quaas, Maria Herberg, Michal R. Schweiger, Gabriela Aust and Joerg Galle
Cells 2021, 10(7), 1718; https://doi.org/10.3390/cells10071718
Available online: https://www.mdpi.com/2073-4409/10/7/1718

"Phagocytic Activities of Reactive Microglia and Astrocytes Associated with Prion Diseases Are Dysregulated in Opposite Directions"
by Anshuman Sinha, Rajesh Kushwaha, Kara Molesworth, Olga Mychko, Natallia Makarava and Ilia V. Baskakov
Cells 2021, 10(7), 1728; https://doi.org/10.3390/cells10071728
Available online: https://www.mdpi.com/2073-4409/10/7/1728

"The Emergence of Senescent Surface Biomarkers as Senotherapeutic Targets"
by Martina Rossi and Kotb Abdelmohsen
Cells 2021, 10(7), 1740; https://doi.org/10.3390/cells10071740
Available online: https://www.mdpi.com/2073-4409/10/7/1740

"Multifunctionality of the Telomere-Capping Shelterin Complex Explained by Variations in Its Protein Composition"
by Claire Ghilain, Eric Gilson and Marie-Josèphe Giraud-Panis
Cells 2021, 10(7), 1753; https://doi.org/10.3390/cells10071753
Available online: https://www.mdpi.com/2073-4409/10/7/1753

"Examining the Role of the Noradrenergic Locus Coeruleus for Predicting Attention and Brain Maintenance in Healthy Old Age and Disease: An MRI Structural Study for the Alzheimer’s Disease Neuroimaging Initiative"
by Emanuele R. G. Plini, Erik O’Hanlon, Rory Boyle, Francesca Sibilia, Gaia Rikhye, Joanne Kenney, Robert Whelan, Michael C. Melnychuk, Ian H. Robertson and Paul M. Dockree
Cells 2021, 10(7), 1829; https://doi.org/10.3390/cells10071829
Available online: https://www.mdpi.com/2073-4409/10/7/1829

"The Influence of Virus Infection on Microglia and Accelerated Brain Aging"
by Luis Filgueira, Alexey Larionov and Nils Lannes
Cells 2021, 10(7), 1836; https://doi.org/10.3390/cells10071836
Available online: https://www.mdpi.com/2073-4409/10/7/1836

"The Glyoxalase System in Age-Related Diseases: Nutritional Intervention as Anti-Ageing Strategy"
by Gemma Aragonès, Sheldon Rowan, Sarah G. Francisco, Elizabeth A. Whitcomb, Wenxin Yang, Giuliana Perini-Villanueva, Casper G. Schalkwijk, Allen Taylor and Eloy Bejarano
Cells 2021, 10(8), 1852; https://doi.org/10.3390/cells10081852
Available online: https://www.mdpi.com/2073-4409/10/8/1852

"Role of NF-κB in Ageing and Age-Related Diseases: Lessons from Genetically Modified Mouse Models"
by Verónica A. García-García, Josefa P. Alameda, Angustias Page and María Llanos Casanova
Cells 2021, 10(8), 1906; https://doi.org/10.3390/cells10081906
Available online: https://www.mdpi.com/2073-4409/10/8/1906

"Neuroinflammation and Alzheimer’s Disease: A Machine Learning Approach to CSF Proteomics"
by Lorenzo Gaetani, Giovanni Bellomo, Lucilla Parnetti, Kaj Blennow, Henrik Zetterberg and Massimiliano Di Filippo
Cells 2021, 10(8), 1930; https://doi.org/10.3390/cells10081930
Available online: https://www.mdpi.com/2073-4409/10/8/1930

"The Interdependency and Co-Regulation of the Vitamin D and Cholesterol Metabolism"
by Tara Warren, Roisin McAllister, Amy Morgan, Taranjit Singh Rai, Victoria McGilligan, Matthew Ennis, Christopher Page, Catriona Kelly, Aaron Peace, Bernard M. Corfel et al.
Cells 2021, 10(8), 2007; https://doi.org/10.3390/cells10082007
Available online: https://www.mdpi.com/2073-4409/10/8/2007

"Applying Bioinformatic Platforms, In Vitro, and In Vivo Functional Assays in the Characterization of Genetic Variants in the GH/IGF Pathway Affecting Growth and Development"
by Sabina Domené, Paula A. Scaglia, Mariana L. Gutiérrez and Horacio M. Domené
Cells 2021, 10(8), 2063; https://doi.org/10.3390/cells10082063
Available online: https://www.mdpi.com/2073-4409/10/8/2063

"Cognitive Impairment in Frail Hypertensive Elderly Patients: Role of Hyperglycemia"
by Pasquale Mone, Jessica Gambardella, Antonella Pansini, Antonio de Donato, Giuseppe Martinelli, Eugenio Boccalone, Alessandro Matarese, Salvatore Frullone and Gaetano Santulli
Cells 2021, 10(8), 2115; https://doi.org/10.3390/cells10082115
Available online: https://www.mdpi.com/2073-4409/10/8/2115

"Beyond Activation: Characterizing Microglial Functional Phenotypes"
by Julia Lier, Wolfgang J. Streit and Ingo Bechmann
Cells 2021, 10(9), 2236; https://doi.org/10.3390/cells10092236
Available online: https://www.mdpi.com/2073-4409/10/9/2236

"MNase Digestion Protection Patterns of the Linker DNA in Chromatosomes"
by Chang-Hui Shen and James Allan
Cells 2021, 10(9), 2239; https://doi.org/10.3390/cells10092239
Available online: https://www.mdpi.com/2073-4409/10/9/2239

"Aging and Cancer: The Waning of Community Bonds"
by Ezio Laconi, Samuele Cheri, Maura Fanti and Fabio Marongiu
Cells 2021, 10(9), 2269; https://doi.org/10.3390/cells10092269
Available online: https://www.mdpi.com/2073-4409/10/9/2269

"Role of Complement in Regulating Inflammation Processes in Renal and Prostate Cancers"
by Giuseppe Stefano Netti, Rossana Franzin, Alessandra Stasi, Federica Spadaccino, Andrea Dello Strologo, Barbara Infante, Loreto Gesualdo, Giuseppe Castellano, Elena Ranieri and Giovanni Stallone
Cells 2021, 10(9), 2426; https://doi.org/10.3390/cells10092426
Available online: https://www.mdpi.com/2073-4409/10/9/2426

"Alpha-Synuclein and Lipids: The Elephant in the Room?"
by Alessia Sarchione, Antoine Marchand, Jean-Marc Taymans and Marie-Christine Chartier-Harlin
Cells 2021, 10(9), 2452; https://doi.org/10.3390/cells10092452
Available online: https://www.mdpi.com/2073-4409/10/9/2452

"Heat Shock Factor 1 Prevents Age-Related Hearing Loss by Decreasing Endoplasmic Reticulum Stress"
by Yun Yeong Lee, Eun Sol Gil, In Hye Jeong, Hantai Kim, Jeong Hun Jang and Yun-Hoon Choung
Cells 2021, 10(9), 2454; https://doi.org/10.3390/cells10092454
Available online: https://www.mdpi.com/2073-4409/10/9/2454

"Potential Therapeutic Candidates for Age-Related Macular Degeneration (AMD)"
by Sonali Nashine
Cells 2021, 10(9), 2483; https://doi.org/10.3390/cells10092483
Available online: https://www.mdpi.com/2073-4409/10/9/2483

"Altered Brain Cholinergic and Synaptic Markers in Obese Zucker Rats"
by Ilenia Martinelli, Daniele Tomassoni, Proshanta Roy, Francesco Amenta and Seyed Khosrow Tayebati
Cells 2021, 10(10), 2528; https://doi.org/10.3390/cells10102528
Available online: https://www.mdpi.com/2073-4409/10/10/2528

"Inflammaging, an Imbalanced Immune Response That Needs to Be Restored for Cancer Prevention and Treatment in the Elderly"
by Juana Serrano-López and Beatriz Martín-Antonio
Cells 2021, 10(10), 2562; https://doi.org/10.3390/cells10102562
Available online: https://www.mdpi.com/2073-4409/10/10/2562

"Role of Aberrantly Activated Lysophosphatidic Acid Receptor 1 Signaling Mediated Inflammation in Renal Aging"
by Yongjie Jin, Eun Nim Kim, Ji Hee Lim, Hyung Duk Kim, Tae Hyun Ban, Chul Woo Yang, Cheol Whee Park and Bum Soon Choi
Cells 2021, 10(10), 2580; https://doi.org/10.3390/cells10102580
Available online: https://www.mdpi.com/2073-4409/10/10/2580

"PI3Kδ Sustains Keratinocyte Hyperproliferation and Epithelial Inflammation: Implications for a Topically Druggable Target in Psoriasis"
by Laura Mercurio, Martina Morelli, Claudia Scarponi, Giovanni Luca Scaglione, Sabatino Pallotta, Cristina Albanesi and Stefania Madonna
Cells 2021, 10(10), 2636; https://doi.org/10.3390/cells10102636
Available online: https://www.mdpi.com/2073-4409/10/10/2636

"Influence of Age and Breed on Bovine Ovarian Capillary Blood Supply, Ovarian Mitochondria and Telomere Length"
by Paweł Kordowitzki, Roswitha Merle, Pascal-Kolja Hass, Johanna Plendl, Juliane Rieger and Sabine Kaessmeyer
Cells 2021, 10(10), 2661; https://doi.org/10.3390/cells10102661
Available online: https://www.mdpi.com/2073-4409/10/10/2661

"The Role of Insulin-like Growth Factor-1 (IGF-1) in the Control of Neuroendocrine Regulation of Growth"
by Sarmed Al-Samerria and Sally Radovick
Cells 2021, 10(10), 2664; https://doi.org/10.3390/cells10102664
Available online: https://www.mdpi.com/2073-4409/10/10/2664

"Identification of Tropical Plant Extracts That Extend Yeast Chronological Life Span"
by Mandy Mun Yee Kwong, Jee Whu Lee, Mohammed Razip Samian, Habibah A. Wahab, Nobumoto Watanabe and Eugene Boon Beng Ong
Cells 2021, 10(10), 2718; https://doi.org/10.3390/cells10102718
Available online: https://www.mdpi.com/2073-4409/10/10/2718

"Cochlear Inflammaging in Relation to Ion Channels and Mitochondrial Functions"
by Parveen Bazard, Jennifer Pineros, Robert D. Frisina, Mark A. Bauer, Alejandro A. Acosta, Lauren R. Paganella, Dominika Borakiewicz, Mark Thivierge, Freyda L. Mannering, Xiaoxia Zhul et al.
Cells 2021, 10(10), 2761; https://doi.org/10.3390/cells10102761
Available online: https://www.mdpi.com/2073-4409/10/10/2761

"Mitochondrial Phospholipid Homeostasis Is Regulated by the i-AAA Protease PaIAP and Affects Organismic Aging"
by Timo Löser, Aljoscha Joppe, Andrea Hamann and Heinz D. Osiewacz
Cells 2021, 10(10), 2775; https://doi.org/10.3390/cells10102775
Available online: https://www.mdpi.com/2073-4409/10/10/2775

"Unexpected Implication of SRP and AGO2 in Parkinson’s Disease: Involvement in Alpha-Synuclein Biogenesis"
by Sarah M. Hernandez, Elena B. Tikhonova, Kristen R. Baca, Fanpeng Zhao, Xiongwei Zhu and Andrey L. Karamyshev
Cells 2021, 10(10), 2792; https://doi.org/10.3390/cells10102792
Available online: https://www.mdpi.com/2073-4409/10/10/2792

"The Cytotoxicity and Clearance of Mutant Huntingtin and Other Misfolded Proteins"
by Austin Folger and Yanchang Wang
Cells 2021, 10(11), 2835; https://doi.org/10.3390/cells10112835
Available online: https://www.mdpi.com/2073-4409/10/11/2835

"Role of Deep Learning in Predicting Aging-Related Diseases: A Scoping Review"
by Jyotsna Talreja Wassan, Huiru Zheng and Haiying Wang
Cells 2021, 10(11), 2924; https://doi.org/10.3390/cells10112924
Available online: https://www.mdpi.com/2073-4409/10/11/2924

"Exosomes in Ageing and Motor Neurone Disease: Biogenesis, Uptake Mechanisms, Modifications in Disease and Uses in the Development of Biomarkers and Therapeutics"
by Ekene Anakor, Laura Le Gall, Julie Dumonceaux, William John Duddy and Stephanie Duguez
Cells 2021, 10(11), 2930; https://doi.org/10.3390/cells10112930
Available online: https://www.mdpi.com/2073-4409/10/11/2930

"Evaluation of Immunomodulatory Responses and Changed Wound Healing in Type 2 Diabetes—A Study Exploiting Dermal Fibroblasts from Diabetic and Non-Diabetic Human Donors"
by Kimberly Nickel, Ursula Wensorra, Horst Wenck, Nils Peters and Harald Genth
Cells 2021, 10(11), 2931; https://doi.org/10.3390/cells10112931
Available online: https://www.mdpi.com/2073-4409/10/11/2931

"Dysregulation of Caveolin-1 Phosphorylation and Nuclear Translocation Is Associated with Senescence Onset"
by Andreas Goutas, Zozo Outskouni, Ioanna Papathanasiou, Maria Satra, George Koliakos and Varvara Trachana
Cells 2021, 10(11), 2939; https://doi.org/10.3390/cells10112939
Available online: https://www.mdpi.com/2073-4409/10/11/2939

"Integrative Analyses Reveal Tstd1 as a Potential Modulator of HDL Cholesterol and Mitochondrial Function in Mice"
by Adi Zheng, Hao Li, Zhihui Feng and Jiankang Liu
Cells 2021, 10(11), 2976; https://doi.org/10.3390/cells10112976
Available online: https://www.mdpi.com/2073-4409/10/11/2976

"Disruption of Mitochondrial Homeostasis: The Role of PINK1 in Parkinson’s Disease"
by Maria Vizziello, Linda Borellini, Giulia Franco and Gianluca Ardolino
Cells 2021, 10(11), 3022; https://doi.org/10.3390/cells10113022
Available online: https://www.mdpi.com/2073-4409/10/11/3022

"GLUT1, GLUT3 Expression and 18FDG-PET/CT in Human Malignant Melanoma: What Relationship Exists? New Insights and Perspectives"
by Gerardo Cazzato, Anna Colagrande, Antonietta Cimmino, Caterina Abbatepaolo, Emilio Bellitti, Paolo Romita, Lucia Lospalluti, Caterina Foti, Francesca Arezzo, Vera Loizzil et al.
Cells 2021, 10(11), 3090; https://doi.org/10.3390/cells10113090
Available online: https://www.mdpi.com/2073-4409/10/11/3090

"Hallmarks of Testicular Aging: The Challenge of Anti-Inflammatory and Antioxidant Therapies Using Natural and/or Pharmacological Compounds to Improve the Physiopathological Status of the Aged Male Gonad"
by María Eugenia Matzkin, Ricardo Saúl Calandra, Soledad Paola Rossi, Andrzej Bartke and Mónica Beatriz Frungieri
Cells 2021, 10(11), 3114; https://doi.org/10.3390/cells10113114
Available online: https://www.mdpi.com/2073-4409/10/11/3114

"Single-Cell Transcriptomics Reveals the Expression of Aging- and Senescence-Associated Genes in Distinct Cancer Cell Populations"
by Dominik Saul and Robyn Laura Kosinsky
Cells 2021, 10(11), 3126; https://doi.org/10.3390/cells10113126
Available online: https://www.mdpi.com/2073-4409/10/11/3126

"Aging-Related Cellular, Structural and Functional Changes in the Lymph Nodes: A Significant Component of Immunosenescence? An Overview"
by Marta Cakala-Jakimowicz, Paulina Kolodziej-Wojnar and Monika Puzianowska-Kuznicka
Cells 2021, 10(11), 3148; https://doi.org/10.3390/cells10113148
Available online: https://www.mdpi.com/2073-4409/10/11/3148

"Pin1 as Molecular Switch in Vascular Endothelium: Notes on Its Putative Role in Age-Associated Vascular Diseases"
by Francesca Fagiani, Marieva Vlachou, Daniele Di Marino, Ilaria Canobbio, Alice Romagnoli, Marco Racchi, Stefano Govoni and Cristina Lanni
Cells 2021, 10(12), 3287; https://doi.org/10.3390/cells10123287
Available online: https://www.mdpi.com/2073-4409/10/12/3287

"Night Photostimulation of Clearance of Beta-Amyloid from Mouse Brain: New Strategies in Preventing Alzheimer’s Disease"
by Oxana Semyachkina-Glushkovskaya, Thomas Penzel, Inna Blokhina, Alexander Khorovodov, Ivan Fedosov, Tingting Yu, Georgy Karandin, Arina Evsukova, Dariya Elovenko, Viktoria Adushkinal.
Cells 2021, 10(12), 3289; https://doi.org/10.3390/cells10123289
Available online: https://www.mdpi.com/2073-4409/10/12/3289

"Senescent Cells in Cancer: Wanted or Unwanted Citizens"
by Sven E. Niklander, Daniel W. Lambert and Keith D. Hunter
Cells 2021, 10(12), 3315; https://doi.org/10.3390/cells10123315
Available online: https://www.mdpi.com/2073-4409/10/12/3315

"Aging of Podospora anserina Leads to Alterations of OXPHOS and the Induction of Non-Mitochondrial Salvage Pathways"
by Verena Warnsmann, Jana Meisterknecht, Ilka Wittig and Heinz D. Osiewacz
Cells 2021, 10(12), 3319; https://doi.org/10.3390/cells10123319
Available online: https://www.mdpi.com/2073-4409/10/12/3319

"Role of Senescence and Aging in SARS-CoV-2 Infection and COVID-19 Disease"
by Seodhna M. Lynch, Guangran Guo, David S. Gibson, Anthony J. Bjourson and Taranjit Singh Rai
Cells 2021, 10(12), 3367; https://doi.org/10.3390/cells10123367
Available online: https://www.mdpi.com/2073-4409/10/12/3367

"Co-Expression of Nogo-A in Dopaminergic Neurons of the Human Substantia Nigra Pars Compacta Is Reduced in Parkinson’s Disease"
by Gian-Carlo Eyer, Stefano Di Santo, Ekkehard Hewer, Lukas Andereggen, Stefanie Seiler and Hans Rudolf Widmer
Cells 2021, 10(12), 3368; https://doi.org/10.3390/cells10123368
Available online: https://www.mdpi.com/2073-4409/10/12/3368

"Association of FOXO3 Blood DNA Methylation with Cancer Risk, Cancer Survival, and Mortality"
by Chenglong Yu, Allison M. Hodge, Ee Ming Wong, Jihoon Eric Joo, Enes Makalic, Daniel Schmidt, Daniel D. Buchanan, John L. Hopper, Graham G. Giles, Melissa C. Southeyl et al.
Cells 2021, 10(12), 3384; https://doi.org/10.3390/cells10123384
Available online: https://www.mdpi.com/2073-4409/10/12/3384

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by Chieh-Yu Shen, Cheng-Hsun Lu, Cheng-Han Wu, Ko-Jen Li, Yu-Min Kuo, Song-Chou Hsieh and Chia-Li Yu
Cells 2021, 10(12), 3402; https://doi.org/10.3390/cells10123402
Available online: https://www.mdpi.com/2073-4409/10/12/3402

"Temporal Profiling of the Cortical Synaptic Mitochondrial Proteome Identifies Ageing Associated Regulators of Stability"
by Laura C. Graham, Rachel A. Kline, Douglas J. Lamont, Thomas H. Gillingwater, Neil A. Mabbott, Paul A. Skehel and Thomas M. Wishart
Cells 2021, 10(12), 3403; https://doi.org/10.3390/cells10123403
Available online: https://www.mdpi.com/2073-4409/10/12/3403

"Cellular Senescence in Adrenocortical Biology and Its Disorders"
by Xin Gao, Faping Li, Bin Liu, Yuxiong Wang, Yishu Wang and Honglan Zhou
Cells 2021, 10(12), 3474; https://doi.org/10.3390/cells10123474
Available online: https://www.mdpi.com/2073-4409/10/12/3474

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by David Mengel, Tze How Mok, Akin Nihat, Wen Liu, Robert A. Rissman, Douglas Galasko, Henrik Zetterberg, Simon Mead, John Collinge and Dominic M. Walsh
Cells 2021, 10(12), 3514; https://doi.org/10.3390/cells10123514
Available online: https://www.mdpi.com/2073-4409/10/12/3514

"Cytosolic Self-DNA—A Potential Source of Chronic Inflammation in Aging"
by Mansour Akbari, Daryl P. Shanley, Vilhelm A. Bohr and Lene Juel Rasmussen
Cells 2021, 10(12), 3544; https://doi.org/10.3390/cells10123544
Available online: https://www.mdpi.com/2073-4409/10/12/3544

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by Alice-Anaïs Varlet, Camille Desgrouas, Cécile Jebane, Nathalie Bonello-Palot, Patrice Bourgeois, Nicolas Levy, Emmanuèle Helfer, Noémie Dubois, René Valero, Catherine Badensl et al.
Cells 2021, 11(1), 50; https://doi.org/10.3390/cells11010050
Available online: https://www.mdpi.com/2073-4409/11/1/50

"The Alpha-Synuclein RT-QuIC Products Generated by the Olfactory Mucosa of Patients with Parkinson’s Disease and Multiple System Atrophy Induce Inflammatory Responses in SH-SY5Y Cells"
by Chiara Maria Giulia De Luca, Alessandra Consonni, Federico Angelo Cazzaniga, Edoardo Bistaffa, Giuseppe Bufano, Giorgia Quitarrini, Luigi Celauro, Giuseppe Legname, Roberto Eleopra, Fulvio Baggil et al.
Cells 2021, 11(1), 87; https://doi.org/10.3390/cells11010087
Available online: https://www.mdpi.com/2073-4409/11/1/87