Biocatalysis-Driven Catalytic Routes for Green and Alternative Chemical Production

Dear Colleagues,

Biocatalysis is increasingly transforming chemical manufacturing by delivering unmatched chemo-, regio-, and stereoselectivity under mild conditions. However, broader industrial adoption requires new catalytic routes that replace energy-intensive, wasteful, or hazardous conventional processes while expanding accessible reactivity. This Special Issue highlights biocatalysis-centered transformations for green and alternative chemical production, with an emphasis on coupling enzymes with complementary catalytic modes to unlock synergistic performance. We welcome original articles and critical reviews covering, but not limited to, enzyme-led coupled, tandem, and cascade processes; chemoenzymatic systems integrating enzymes with metal catalysis (homogeneous, heterogeneous, or biohybrid); and photobiocatalysis and enzyme–photocatalyst coupling for novel bond formations and selective redox chemistry. We also seek submissions on electrobiocatalysis and enzyme–electrocatalyst coupling for cofactor regeneration and redox-intensive conversions, as well as integrated one-pot and flow processes, immobilization, and process intensification. Contributions that demonstrate credible greener alternatives to established synthetic routes—supported by mechanistic insight, quantitative sustainability metrics, and/or scalable process concepts—are particularly encouraged.

If you would like to submit papers to this Special Issue or have any questions, please contact the in-house editor, Ms. Rita Lin (rita.lin@mdpi.com).

Dr. Kaili Nie
Dr. Junfeng Liu
Guest Editors

Manuscript Submission Information

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