Circulating miRNAs as Tumor Biomarkers

Dear Colleagues,

miRNAs are short non-coding RNA molecules that regulate mRNA expression post-transcriptionally. These molecules are being excreted extracellularly and detected in many types of body fluids, such as blood, urine, etc. The presence of circulating miRNAs in peripheral blood in a highly stable manner has positioned them as promising noninvasive new biomarkers for a wide range of diagnostic applications. Their role has been studied extensively mainly on diagnosis, prognosis, and resistance to therapy for several types of human cancers.

This Special Issue will highlight the clinical importance of circulating miRNAs as biomarkers, the effects of various preanalytical and analytical parameters on their measurements, as well as technological advances that will further improve our knowledge in the field of early diagnosis and detection of minimal residual disease.

Dr. Athina N. Markou
Guest Editor

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