Alcohol Use and Cancer Risk
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Epidemiology and Prevention".
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 4545
Special Issue Editors
Interests: carcinogenesis; gastrointestinal cancers; cancer screening
Interests: alcohol metabolism and toxicity; carcinogenesis; liver disease;
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Alcohol use is a major and potentially modifiable risk factor for cancers. The longer and the more a person drinks, the higher the risk of cancer becomes. Cancer incidence due to chronic alcohol consumption increases worldwide. In 2002, alcohol was responsible for 3.6% of all cancers, which increased significantly to 5.5% in 2012. In 2016, 368,000 cancer deaths worldwide were attributable to alcohol use. In 2007, the International Agency for Research on Cancer declared alcohol as a carcinogen and stated: Alcoholic beverages are carcinogenic to humans. Today, alcohol is recognized to be a risk factor for cancers of the oral mucosa, the pharynx, the larynx, the squamous cell esophageal mucosa, the stomach, the liver, the colorectum, the female breast, and (most likely) the pancreas.
Although an epidemiological link between alcohol consumption and cancer has been known for more than 100 years, the unraveling of the underlying pathophysiology and mechanisms of alcohol-mediated carcinogenesis is still ongoing. Definitively, acetaldehyde derived from alcohol plays a major role in alcohol-induced carcinogenesis.
This Special issue of Cancers focuses on epidemiology, mechanisms, synergistic risk factors, and finally target organs of alcohol-mediated carcinogenesis, including recommendations for cancer screening in high-risk users. Leading world experts in the field will present up-to-date data for a broad spectrum of readership.
Prof. Dr. Hans Scherubl
Prof. Dr. Helmut K. Seitz
Guest Editors
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Keywords
- alcohol use
- cancer
- tumor
- malignancy
- neoplasm
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