Female Malignancies and Immunotherapy: What’s New?
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Immunology and Immunotherapy".
Deadline for manuscript submissions: closed (30 April 2021) | Viewed by 15629
Special Issue Editors
Interests: human immunology; innate immunity; human natural killer cells; tumor immunology; immunotherapy; immune checkpoints
Special Issues, Collections and Topics in MDPI journals
2. Anatomic Pathology University Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy
Interests: gynecologic pathology; placental & fetal pathology; molecular pathology
Special Issues, Collections and Topics in MDPI journals
Interests: human natural killer cells; NK cell receptors; activating NK receptors; NKG2A; KIRs; PD-1; cancer immunosurveillance; cancer biology; tumor microenvironment; microRNAs; immunotherapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Current emerging therapies for solid tumors include various immunotherapeutic approaches, like immune checkpoint inhibitors (ICIs)(1), that have gained considerable attention because of their impressive treatment outcomes in different tumor types. Unfortunately, benefits have been seen only in a small percentage of patients with solid tumors. For this reason, it is strictly necessary to implement our knowledge on immune checkpoints (ICs) and on the tumor microenvironment.
In the cancer treatment context, T cells have always been considered to be primarily responsible for the beneficial effect of immunotherapy. However, NK cells are also now seen as a promising cancer immunotherapy tool, due to their ability to kill malignant cells without toxicity towards healthy cells. However, cancers develop escape strategies to alter immune cells’ anti-tumor activity.
Among existing cancers, female malignancies represent annoyances in terms of diagnosis and clinical approaches efficacy. Indeed, female tumors are often characterized by an immunosuppressive tumor environment, able to resist not only an immune system attack, but also advanced immunotherapeutic approaches. The scope of this Special Issue is to contribute to dissecting the molecular and cellular immunological mechanisms involved in female malignancies’ progression and metastasis. This information will provide new insights that are crucial for the development of new immunotherapeutic strategies and for the improvement of combination strategies in patient-specific female cancers’ treatments.
Dr. Silvia Pesce
Prof. Valerio Gaetano Vellone
Prof. Emanuela Marcenaro
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- breast
- ovarian and cervical and uterine oncology
- natural killer cells
- immunotherapy
- cancer immunology
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.