Endoscopic Management of Gastrointestinal, Hepatobiliary and Pancreatic Malignancies

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Methods and Technologies Development".

Deadline for manuscript submissions: closed (1 February 2024) | Viewed by 3660

Special Issue Editors


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Guest Editor
1. Division of Pediatric Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA 94305, USA
2. Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA 94305, USA
Interests: interventional endoscopy; gastroenterology; pediatric interventional endoscopy; biliary and pancreatic disorders in adults and children

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Guest Editor
1. UCLA-Olive View, Division of Gastroenterology, Sylmar, CA 91342, USA
2. David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
Interests: gastrointestinal endoscopy; cholangiopathies; biliary tract neoplasms; biomedical technology; multimodal imaging; minority health; healthcare disparities

Special Issue Information

Dear Colleagues,

Endoscopic management has become a cornerstone in the clinical care of patients with gastrointestinal, hepatobiliary and pancreatic malignancies, and its role in this regard continues to expand. These malignancies constitute a large, heterogeneous, and impactful group of diseases and, as such, the benefits of endoscopy as a minimally invasive platform, be it in diagnosis, staging, curative treatment, or palliation, are far-reaching at an individual and public health level. Despite the fact that endoscopic management used to be limited to diagnostic luminal endoscopy, modalities and interventions such as endoscopic ultrasound, endoscopic retrograde cholangiopancreatography, cholangioscopy, stenting, ablation, resection, etc., have opened new horizons and paved vital care pathways for patients. These, in turn, can be coupled with various multi-disciplinary approaches to optimize clinical outcomes.

This Special Issue aims to highlight the advances, challenges, and trends in the endoscopic management of gastrointestinal, hepatobiliary, and pancreatic malignancies, with the aim of improving and expanding existing approaches, inspiring new ones, and providing greater options for patients with these malignancies.

Dr. Monique T. Barakat
Dr. James H. Tabibian
Guest Editors

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Keywords

  • adenocarcinoma
  • lymphoma
  • squamous cell carcinoma
  • biliary tract diseases
  • endoscopic resection
  • palliative therapy
  • population health
  • ERCP
  • EUS

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Published Papers (2 papers)

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Research

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9 pages, 585 KiB  
Article
Tertiary Care Center Trends in Colonic Stent Placement over the Past Decade
by Wassem Y. Juakiem, Kelita Singh, Andrew Ofosu, Daryl Ramai, Alana Persaud, James H. Tabibian, Eduardo Rodrigues-Pinto, Mohit Girotra and Monique T. Barakat
Cancers 2024, 16(19), 3309; https://doi.org/10.3390/cancers16193309 - 27 Sep 2024
Cited by 2 | Viewed by 844
Abstract
Introduction: Colonic endoluminal stent placement is a commonly utilized and effective endoscopic approach for the management of malignant large bowel obstruction and is an emerging approach for the management of some benign etiologies of large bowel obstruction. However, recent studies evaluating the evolution [...] Read more.
Introduction: Colonic endoluminal stent placement is a commonly utilized and effective endoscopic approach for the management of malignant large bowel obstruction and is an emerging approach for the management of some benign etiologies of large bowel obstruction. However, recent studies evaluating the evolution of clinical scenarios and patient populations for which stenting is performed in real-world practice are lacking. Methods: We assessed colonic stent utilization patterns in a tertiary care academic medical center over the past 10 years. We analyzed the demographics and patient and procedure characteristics of the initial (first half of study period) and latter (second half of the study period) procedures to assess trends over time using standard descriptive statistics. Results: Our analysis was notable due to its provision of some novel insights. The frequency of colonic stent placement procedures increased significantly over time by comparison of the procedure volume for the initial 5-year interval (22 colonic stent procedures) relative to the latter 5-year interval (49 colonic stent procedures) (p = 0.03). The median age of patients who underwent colonic stent placement was significantly lower in the latter 5 years, compared with the initial 5 years of the study period (mean of 81.41 vs. 58.73 years, respectively, p < 0.001). The increased diversity of indications for colonic stent placement was also noted over time. Conclusions: Our data highlight the evolution of colonic stent placement in tertiary care practice over time and are notable for some interesting trends, including the increased utilization of colonic stent placement over time, the broadening of indications for colonic stent placement to include benign indications, and lower patient age at the time of colonic stent placement over time. These findings will help inform the clinical practice of colonic stent placement and provide a foundation to guide future research on the topic. Full article
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Review

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12 pages, 773 KiB  
Review
Endoscopic Treatment of Malignant Hilar Biliary Obstruction
by Jakub Pietrzak and Adam Przybyłkowski
Cancers 2023, 15(24), 5819; https://doi.org/10.3390/cancers15245819 - 13 Dec 2023
Cited by 4 | Viewed by 2412
Abstract
Stent implantation is an effective approach for palliative treatment of Bismuth-Corlette type III–IV malignant hilar biliary obstructions (MHBOs). In this article, we reviewed the currently used access methods for biliary stent placement (percutaneous transhepatic biliary drainage, endoscopic biliary drainage, endosonography guided biliary drainage), [...] Read more.
Stent implantation is an effective approach for palliative treatment of Bismuth-Corlette type III–IV malignant hilar biliary obstructions (MHBOs). In this article, we reviewed the currently used access methods for biliary stent placement (percutaneous transhepatic biliary drainage, endoscopic biliary drainage, endosonography guided biliary drainage), the available stent types (plastic stent, self-expanding metallic stent, full cover self-expanding metallic stent, radioactive self-expanding metallic stent), major approaches (unilateral, bilateral) and deployment methods (stent-in-stent, stent-by-stent). Finally, this review gives an outlook on perspectives of development in stenting and other palliative methods in MHBO. Full article
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