Special Issue "Bioengineering and Cancer"

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Clinical Trials of Cancer".

Deadline for manuscript submissions: 30 April 2022.

Special Issue Editor

Dr. Daniela Loessner
E-Mail Website
Guest Editor
1. Department of Chemical Engineering and Department of Materials Science and Engineering, Faculty of Engineering, Monash University, Melbourne, VIC 3800, Australia
2. Department of Anatomy and Developmental Biology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, VIC 3800, Australia
Interests: tissue engineering; biomaterials; tumour microenvironment; cell and matrix biology; 3D cancer models

Special Issue Information

Dear Colleagues,

Biomimetic tissue-engineered technologies have produced contemporary tools for research into cancer. Biomaterial-based 3D cancer models harbor the dimensionality and biochemical and mechanical properties of tumor tissues. Although biomaterials mimic the architecture and composition of tumor-associated extracellular matrices and cell functions as seen in patient tumors, to date, only a minority of 3D cancer cell cultures are based on these instructive materials. This is likely caused by the level of complexity and difficulty of using these models, as well as the limited or cumbersome analytical techniques and validation. However, there is an increasing dialog between life scientists and engineers. Most 3D approaches utilize reconstituted matrices that originate from murine tumors, containing murine proteins in undefined amounts, or rat-derived collagen. Novel 3D models require complementary and multi-disciplinary partnerships in tumor biology, physical sciences, and additive manufacturing. This Special Issue will highlight applications and challenges of tissue-engineered platforms, including multi-component and 3D-bioprinted approaches, such as 3D tumor and metastasis models.

Dr. Daniela Loessner
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • tissue engineering
  • tumour biology
  • biomechanics
  • functional materials
  • extracellular matrix
  • hydrogels
  • scaffolds
  • 3D bioprinting
  • cancer cells
  • metastasis

Published Papers

This special issue is now open for submission.
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