Osteosarcoma: Individualized Precision Treatment and Effective Drug Discovery
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Drug Development".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 83
Special Issue Editor
Interests: osteosarcoma; bone cancer; tumor microenvironment; tumor acidosis; lipid metabolism; targeted therapies; precision medicine; microfluidics; 3D tumor models
Special Issue Information
Dear Colleagues,
Osteosarcoma is a highly aggressive cancer of mesenchymal origin that develops in bone. Despite decades of research, the survival rates for patients with osteosarcoma have remained largely unchanged. While surgery and conventional therapies remain the cornerstone of treatment, they offer limited benefits for patients with metastatic disease. This underscores the urgent need for innovative therapies to improve survival rates and reduce metastatic spread.
This Special Issue seeks to explore the latest advancements and future directions in understanding the molecular mechanisms underlying bone and soft tissue sarcomas. By delving into the molecular landscape of these tumors, we aim to highlight novel therapeutic strategies and their potential to transform the treatment of these challenging diseases.
Recent years have witnessed remarkable progress in targeted therapies and drug discovery for osteosarcoma. Advances in the molecular characterization of the disease have unveiled promising new targets and treatment avenues.
In this Special Issue, we bring together cutting-edge research and insights to summarize recent breakthroughs in precision medicine and innovative drug discovery for osteosarcoma, offering hope for improved patient outcomes and a brighter future in the fight against this formidable malignancy.
Dr. Margherita Cortini
Guest Editor
Manuscript Submission Information
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Keywords
- osteosarcoma
- bone cancer
- tumor microenvironment
- targeted therapies
- precision medicine
- 3D tumor models
- drug screening
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