Advanced Techniques for Deep Brain Stimulation Treatment of Neurodegenerative Disorders - Series 2

Dear Colleagues,

After more than 25 years of deep brain stimulation and related research, new technological and methodological approaches are now either available or under development with the promise of improved personalization, better outcomes, and earlier application of this neuromodulatory therapy.

Technological advances span from new segmented or multipolar electrodes to new “smart” hardware with closed loop capabilities, based on deep brain signals, cortical signals, neurochemical sensors, movement sensors, or external devices connected to the implanted pulse generator. In addition to these, consumer technologies like smartphones, smart-watches, wearable devices, glasses for mixed reality are more and more allowing the collection of real-life data that could ground the introduction of precision approaches and advanced characterization of the diseases, also in neurodegenerative disorders.

We therefore invite colleagues to contribute to this Special Issue, sharing their expertise in order to build up a state-of-the-art landscape on advanced DBS techniques and methodologies, including technological innovations as well as clinical practice innovations coming from the application of novel devices or systems.

Prof. Sara Marceglia
Prof. Ioannis U. Isaias
Guest Editors

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• Adaptive DBS
• Data driven Approaches
• Personalized Therapy
• Parkinson’s Disease and Related Disorders
• Neuromodulation