Recent Advances in Biosensing Technologies for Single Cell Analysis
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensors and Healthcare".
Deadline for manuscript submissions: closed (30 September 2025) | Viewed by 1307
Special Issue Editors
Interests: droplet microfluidics; biosensor; electrochemistry; cell culture; organoid; robotics; MEMS
Interests: chemical biology; medicinal chemistry; DNA nanotechnology; multiscale simulation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Single-cell analysis is an important technology in the field of cell biology and biomedicine. It highly promotes the understanding of cellular heterogeneity, cell–cell interactions and intracellular changes at the nano/micro scale. In the last several decades, a variety of biosensing technologies have been developed to profile biochemical/biophysical information at the single-cell level such as high-resolution fluorescence imaging, single-cell sequencing, flow cytometry, scanning electrochemical microscopy and microfluidic systems, etc. These technologies for single-cell analysis have been widely utilized in disease diagnosis, bioengineering, drug screen and biological therapy. Nevertheless, several challenges remain, especially as regards developing high-throughput, low-cytotoxicity, high-time-resolution and high-spatial-resolution biosensing technologies for single-cell analysis. In addition, with the rapid expansion of data and information acquired in single-cell detection, introducing the latest achievements from information science such as machine learning, computer vision and cloud computing for processing of the single cell data has received increasing attentions, as these techniques can significantly increase the efficiency of data analysis and enable the extraction of crucial features.
This Special Issue focus on the cutting-edge biosensing technologies for single-cell analysis. We welcome original works, perspectives, and reviews including, but not limited to, the development and applications of sensing technologies, data-processing methods, microfluidic devices and instruments for single-cell analysis.
Dr. Zhen Gu
Dr. Zhi-bei Qu
Guest Editors
Manuscript Submission Information
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