Advances in Multiplex Lateral Flow Biosensors for Simultaneous Biomarker Detection
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensors and Healthcare".
Deadline for manuscript submissions: 30 November 2026 | Viewed by 87
Special Issue Editors
Interests: immunoassay lateral flow; molecular diagnosis; aptamers; peptide nucleic acid
Interests: aptamer; lateral flow assay
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Lateral flow biosensors are rapid and portable diagnostic tools widely used for point-of-care testing because they are inexpensive, simple to use, and provide quick results. Recent technological developments have significantly improved their sensitivity, accuracy, and overall performance. Nanomaterials such as gold nanoparticles, quantum dots, and carbon nanotubes are now commonly used to enhance signal intensity and detection sensitivity, making it possible to detect very low concentrations of biological markers.
Another important advancement is the integration of gene-editing technologies like CRISPR-Cas12 and CRISPR-Cas13 with lateral flow assays, which enables highly specific detection of nucleic acids and rapid identification of pathogens. In addition, multiplex detection allows several targets to be detected on a single test strip, improving diagnostic efficiency. Smartphone-based readout systems also allow digital analysis of results, increasing accuracy and enabling data storage and remote monitoring.
Overall, these advancements have expanded the applications of lateral flow biosensors in areas such as medical diagnostics, food safety, and environmental monitoring, and ongoing research continues to improve their sensitivity, reliability, and accessibility.
Dr. Satheesh Natarajan
Prof. Dr. Maria C DeRosa
Guest Editors
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Keywords
- lateral flow assay
- immunoassay
- molecular diagnosis
- nanomaterials
- additive manufacturing
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