Genetically Encoded Biosensors for Biomedical Applications

Dear Colleagues,

Genetically encoded biosensors (GEBs) have revolutionized modern science. Sensing and measuring biochemical changes within a cellular compartment or specific cell type in a transgenic organism without perturbing the metabolism of the experimental subject have always been difficult for scientists. By following the discovery of fluorescent and bioluminescent proteins, as well as bringing microscopy and directed molecular evolution techniques to the next level, the development of advanced genetically encoded biosensors became possible. Scientists from around the world have put tremendous effort into the creation of GEBs that measure concentrations and activity levels of molecules or ions. The research is steadily approaching to the point where genetically encoded biosensors will be routinely used to monitor long-term signaling processes during the development, disease progression, and aging of a transgenic organism. 

We encourage you to share your findings and ideas in the field of genetically encoded biosensors. This Special Issue will cover all possible types of current GEBs, challenges in their design, a plethora of their applications across scales, their multiplexing, tools required to work with GEBs, and future outlooks. In light of the COVID-19 pandemic, researchers are welcome to share their ideas and discoveries on how genetically encoded biosensors could be used in drug discovery.

Dr. Mikhail Baloban
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.