Luminescent Complexes in Bioimaging, Biosensing and Biomedicine Applications
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Optical and Photonic Biosensors".
Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 187
Special Issue Editor
Special Issue Information
Dear Colleagues,
In the past decade, phosphorescent metal complexes have attracted growing attention as a highly promising class of emitters for bioimaging, biosensing, medical diagnostics and therapy, or in combination as theranostics. Compared to traditional fluorescent organic chromophores, these compounds display a large Stokes shift and long excited state lifetimes that enable cutting off the autofluorescence of endogenous fluorophores, obtaining high spatio-temporal resolution in microscopic imaging, and substantially increasing sensors’ sensitivity to external stimuli. Simultaneously, the development of time-resolved techniques such as phosphorescence lifetime imaging (PLIM) substantially improves detection sensitivity and accuracy, thus making biomedical experiments more convenient and providing valuable information on the physiological status of the objects under study. Metal-complex-based chromophores also display higher photostability and essentially easier chemistry in terms of modifying their properties and fine-tuning their photophysical characteristics by rearranging their ligand environment using typical coordination chemistry methods. These features of luminescent metal complexes have already led to their widespread use in modern biomedical research, which is expected to grow even more. This Special Issue will cover recent advances in the design, preparation, and application of luminescent metal complexes in biology and experimental medicine. Manuscripts related to the development of advanced imaging techniques using metal complexes also fit the topic well.
Full papers, communications, and reviews are welcome.
Prof. Dr. Sergey P. Tunik
Guest Editor
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Keywords
- metal complexes
- phosphorescence
- luminescent microscopy
- bioimaging
- biosensing
- lifetime imaging
- theranostics
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