Special Issue "Molecularly Imprinted Polymers for Chemical Sensing"

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 1569

Special Issue Editors

School of Health Sciences & Technology (SoHST), University of Petroleum and Energy Studies (UPES), Bidholi, Dehradun 248007, India
Interests: molecularly imprinted polymers (MIP); chemical sensors; nanomaterials; gas sensors; biomedical applications; environmental monitoring
Prof. Dr. Bansi Dhar Malhotra
E-Mail Website
Guest Editor
Biomedical Instrumentation Section, CSIR-National Physical Laboratory, Dr. K.S. Krishnan Road, New Delhi-1112, India
Interests: biosensors; biomaterials; bio-molecular electronics; conducting polymers; cancer diagnostics; ordered molecular assemblies; nano-materials; langmuir; odgett films nano-composite based gas sensors
Dr. Po-Kang Yang
E-Mail Website
Guest Editor
Department of Biomedical Sciences and Engineering, National Central University, Chung-li 32001, Taiwan
Interests: nano materials; intelligent sensing; energy technology; soft electronics; semiconductor components
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Special Issue Information

Dear Colleagues,

Molecularly imprinted polymers (MIP) are artificial receptors with excellent selectivity and affinity toward the target analyte. They are generally prepared via self-assembly of monomers or using a crosslinker to form a polymeric matrix around the target. Further elution of the target generates molecular mimicking recognition sites in the matrix that are very specific to the targets in the sample. The MIP has the advantages of low cost, high stability, and high selectivity over enzymes or antibodies-based sensors. In recent years, MIP technology has shown its excellent role in biomedical sensing, but they are at a budding phase in terms of chemical sensing. Chemicals such as gases produced in explosives, over-used pesticides, and the food industry are the main areas of concern in environment and health monitoring. In the last few years, MIP technology has been addressing this issue, and studies have been conducted to develop MIP-based sensors for chemical detection.

Our Special Issue will promote research in this area and invites studies conducted on MIP chemical sensing technology. Specifically, this issue welcomes studies on MIP-based electrochemical, optical, or colorimetric chemical sensors that can be applied to detect: (i) food spoilage/ripening, (ii) toxic gases, i.e., CO, H2S, (iii) gas pesticides, (iv) volatile organic compounds (VOCs), and (v) disease biomarkers. In addition, studies on nanomaterials-MIP-based chemical sensors are welcome in this Special Issue. Article types accepted in this issue include original research, reviews, systematic reviews, meta-analyses, short communications, and perspectives.

Dr. Utkarsh Jain
Prof. Dr. Bansi Dhar Malhotra
Dr. Po-Kang Yang
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • molecularly imprinted polymers (MIP)
  • chemical sensors
  • nanomaterials
  • gas sensors
  • biomedical applications
  • environmental monitoring

Published Papers (1 paper)

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Biomimetic Electrochemical Sensors Based on Core-Shell Imprinted Polymers for Targeted Sunset Yellow Estimation in Environmental Samples
Biosensors 2023, 13(4), 429; https://doi.org/10.3390/bios13040429 - 28 Mar 2023
Cited by 2 | Viewed by 1187
Magnetic molecularly imprinted polymers (MMIPs) contain the predesigned specialized recognition capability that can be chosen to build credible functional materials, that are easy to handle and have a good degree of specificity. Hence, the given piece of work is intended to design a [...] Read more.
Magnetic molecularly imprinted polymers (MMIPs) contain the predesigned specialized recognition capability that can be chosen to build credible functional materials, that are easy to handle and have a good degree of specificity. Hence, the given piece of work is intended to design a novel electrochemical sensor incorporating magnetite-based molecularly imprinted polymers. The building materials consisted of a cross-linker (EGDMA), reaction-initiator (AIBN), monomer (methylene succinic acid-MSA), and template molecule (Sunset Yellow-SY dye). MMIPs exhibited a diameter of 57 nm with an irregular shape due to the presence of cavities based on SEM analysis. XRD patterns exhibited crystallinity, as well as amorphous peaks that are attributed to polymeric and non-polymeric frameworks of MMIPs. The crystallite size of the MMIPs from XRD analysis was found to be 16.28 nm based on the Debye-Scherrer’s equation. Meanwhile, the FTIR bands showed the synthesis of MMIPs using monomer and methylene succinic acid. The sorption data at the optimized operating conditions (pH 2, sorbent dosage 3 mg, time 18 min) showed the highest sorption capacity of 40 mg/g. The obtained data best fitted to the Langmuir sorption isotherm and followed the pseudo-second-order kinetics. The magneto-sensors were applied for ultrasensitive, rapid, and simple sensing of SY dye. The electrochemical experiments were run at the operating condition range of (scan rate 10–50 mV/s, tads 0–120 s, pH 5–9, potential range 1–1.5 V for CV and 1–1.3 V for SWAdASV). The linear range of detection was set to 1.51 × 10−6 M to 1.51 × 10−6 M posing LOD and LOQ values of 8.6242 × 10−5 M and 0.0002874 M, respectively. The regression analysis value for the calibration was found to be 0.950. Additionally, high adsorption efficiency, selectivity, reusability, and strong structural stability of the magneto-sensors showed potential use for SY detection in real samples. These characteristics make MMIPs a viable electrochemical substrate for the detection of chemical contaminants in the environment and in health-related products. Full article
(This article belongs to the Special Issue Molecularly Imprinted Polymers for Chemical Sensing)
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