Novel Graphene-Based Biosensors for Biomedical Applications

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensors and Healthcare".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 1085

Special Issue Editor


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Guest Editor
Institute of Biotechnology and Molecular Medicine, Kampinoska 25, 80-180 Gdańsk, Poland
Interests: biosensors; novel diagnostic techniques

Special Issue Information

Dear Colleagues,

The primary objective of this Special Issue is to gather cutting-edge research on the design, fabrication, and characterization of novel graphene-based biosensors. Contributions are sought that elucidate the underlying principles, methodologies, and applications of these biosensors in various biomedical domains, including, but not limited to, medical diagnostics, therapeutics, drug discovery, and point-of-care testing.

Dr. Sabina Żołędowska
Guest Editor

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Keywords

  • biosensors
  • graphene
  • biomedical applications
  • electrochemical sensing
  • surface modification
  • sensing mechanisms
  • transduction principles
  • medical diagnostics
  • point-of-care testing
  • biomarker detection
  • drug discovery
  • functionalization
  • nanoparticle integration
  • sensitivity
  • specificity
  • stability
  • performance evaluation
  • validation
  • biocompatibility
  • clinical translation

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Published Papers (1 paper)

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Review

24 pages, 3719 KiB  
Review
Recent Advances in Electrochemical Biosensors for Neurodegenerative Disease Biomarkers
by Mingyu Bae, Nayoung Kim, Euni Cho, Taek Lee and Jin-Ho Lee
Biosensors 2025, 15(3), 151; https://doi.org/10.3390/bios15030151 - 28 Feb 2025
Viewed by 818
Abstract
Neurodegenerative diseases, such as Parkinson’s disease (PD) and Alzheimer’s disease (AD), represent a growing global health challenge with overlapping biomarkers. Key biomarkers, including α-synucleins, amyloid-β, and Tau proteins, are critical for accurate detection but are often assessed using conventional methods like enzyme-linked immunosorbent [...] Read more.
Neurodegenerative diseases, such as Parkinson’s disease (PD) and Alzheimer’s disease (AD), represent a growing global health challenge with overlapping biomarkers. Key biomarkers, including α-synucleins, amyloid-β, and Tau proteins, are critical for accurate detection but are often assessed using conventional methods like enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR), which are invasive, costly, and time-intensive. Electrochemical biosensors have emerged as promising tools for biomarker detection due to their high sensitivity, rapid response, and potential for miniaturization. The integration of nanomaterials has further enhanced their performance, improving sensitivity, specificity, and practical application. To this end, this review provides a comprehensive overview of recent advances in electrochemical biosensors for detecting neurodegenerative disease biomarkers, highlighting their strengths, limitations, and future opportunities. By addressing the challenges of early diagnosis, this work aims to stimulate interdisciplinary innovation and improve clinical outcomes for neurodegenerative disease patients. Full article
(This article belongs to the Special Issue Novel Graphene-Based Biosensors for Biomedical Applications)
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