Experimental and Bioinformatic Approaches for Biomarker Discovery in Disease: From Molecular Mechanisms to Therapeutic Challenges
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Bioinformatics and Systems Biology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 1291
Special Issue Editors
Interests: cancer biology; microRNAs; epigenetics; apoptosis and differentiation; platelets; inflammation; cell-to-cell crosstalk; bioactive lipids
Special Issues, Collections and Topics in MDPI journals
Interests: platelets; oxidative stress; cancer; vitamin C; blood coagulation; inflammation; apoptosis; bioactive lipids; redox-sensitive transcription factors; microRNAs
Special Issues, Collections and Topics in MDPI journals
Interests: cancer biology; gene expression; stem cells; veterinary medicine; tissue engineering; epigenetic reprogramming; epigenetic therapy; histone code; histone modification; cancer cell metabolism
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The discovery of biomarkers (genes, transcripts, proteins, metabolites, and non-coding regulatory RNAs) in disease is crucial for enhancing early detection, determining prognosis, selecting therapeutic strategies, and monitoring treatment response. In the past decade, advancements in molecular biology and bioinformatics have significantly accelerated the identification and validation of potential markers. This Special Issue delves into how experimental data, cutting-edge technologies, and computational tools can be integrated to elucidate the molecular mechanisms underlying specific diseases, thus leading to the discovery of novel biomarkers. Both experimental approaches and omics technologies have generated a wealth of biological data, often hindering our ability to understand the relationships between observed molecular changes and disease states, as well as interindividual variability. Bioinformatics analysis serves as a crucial bridge, enabling researchers to interpret data (from public repositories, research projects, and experimental studies) and identify significant molecular patterns, thereby providing a comprehensive understanding of the interaction networks involved in disease onset and progression. This multi-faceted approach is an indispensable prerequisite for translating basic scientific knowledge into clinical research, a process commonly referred to as the “bench-to-bedside” process. We believe that this proposed Special Issue offers a valuable resource for scientists, clinicians, and researchers interested in the forefront of biomarker research.
Dr. Valeria Gasperi
Dr. Maria Valeria Catani
Dr. Alessandra Gambacurta
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- biomarker
- molecular biology
- bioinformatics
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