Biochemical Bases of TRP Channel Functions
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Cellular Biochemistry".
Deadline for manuscript submissions: closed (15 June 2022) | Viewed by 260
Special Issue Editors
Interests: TRP channels; pain; inflammation; peripheral nerve terminals; morpho-functional plasticity; electrophysiology; opto-pharmacology, cornea
Interests: TRP channels; voltage-gated channels; membrane biophysics; electrophysiology; mathematical modeling; pharmacology; signal transduction; pain; inflammation; chemosensation; taste; cardiovascular function; bladder function; innate immunity; neuro-immune interactions; epithelial function; nanotoxicology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
A Special Issue titled “Biochemical Bases of TRP Channel Functions” is being prepared for the journal Biomolecules.
Transient receptor potential (TRP) cation channels are expressed in many different tissues and cell types, being involved in a diversity of biological processes, such as chemo-, mechano- and thermo-sensation and ionic homeostasis. Furthermore, alterations of their functions are responsible for a multitude of inherited and acquired human diseases. A variety of mechanisms have been shown to activate TRP channels, including ligand binding, membrane depolarization, temperature and mechanical changes and covalent modification of nucleophilic residues. Identification and functional studies of TRP channels have been performed over the years using in vitro and in vivo systems, but only recently have solutions for several structures of these ion channels paved the way for further investigations. Original manuscripts and reviews dealing with any aspect of the biochemical bases of TRP channel functions and related pathophysiology are very welcome.
Dr. Victor Meseguer
Dr. Karel Talavera
Guest Editors
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Keywords
- TRP channels
- TRP structure
- TRP functional properties
- TRP structure–function relationship
- TRPs in pathophysiology
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