Recent Advance of Melatonin
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: closed (30 June 2020) | Viewed by 34075
Special Issue Editor
Interests: regulation of biological clock; degenerative neural diseases; regulation of clock-clontrolled genes by melatonin; anti-aging process in neural tissue by melatonin; melatonin effect in ASD during developmental stages
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Melatonin is a hormone produced by the pineal gland and is a potent-free radical scavenger and antioxidant. It scavenges reactive oxygen species (ROS) and reactive nitrogen species (RNS), stimulates the activity of antioxidant enzymes, inhibits proinflammatory cytokines, and activates adhesion molecules in various tissues. In the last few decades, there has been notable progress in understanding the molecular and cellular basis of the complex process of biogenesis of melatonin and its derivatives. Melatonin can preserve the levels of glutathione (GSH) in the mitochondria of the the cell, which help to suppress oxidative damage, resulting in cellular senescence. Accumulated scientific evidence supports that melatonin attenuates not only oxidative damage in neural tissues during developmental stages but also in parenchymal tissues of vital organs. In this Special Issue titled “Recent Advances in Melatonin”, we will deal with the underlying molecular–cellular–biochemical involvement of melatonin not only in homeostasis but also in allostasis of human pathophysiology. Here, we would like to gather manuscripts focused on recently updated research on melatonin and its related areas.
Prof. Yonggeun Hong
Guest Editor
Manuscript Submission Information
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Keywords
- homeostasis and allostasis of melatonin
- role of melatonin in degenerative diseases
- mitochondrial relevance of melatonin
- cognition exaltation by melatonin
- application of phytomelatonin
- melatonin biosynthesis
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