Dynamic Biomolecules in Neurodegeneration: From Structural Mechanisms to Drug Discovery
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 7221
Special Issue Editor
Interests: NMR; Abeta; Alzheimer’s disease; tau; drug discovery; p53; Hedgehog; glycan; sulfating
Special Issue Information
Dear Colleagues,
Neurodegenerative diseases, such as Alzheimer’s disease and related dementia, have tremendous societal impacts, affecting millions of people worldwide. However, few disease-modifying therapeutic options are available, underlying the urgent need for a better understanding of the molecular mechanisms of neurodegeneration. Neurodegenerative pathologies often feature highly flexible molecules, such as amyloid b-peptide, tau, a-synuclein, and glycan, which pose a particular challenge for structural characterization and drug discovery. NMR and computational biology are especially suited to these molecules, due to their unique ability to study molecular dynamics at high resolution. NMR and simulation are also indispensable tools for drug discovery against flexible molecules. In this Special Issue, I would like to invite you to submit your latest results and insights in this area of research, either as an original research article or a review paper.
Prof. Dr. Chunyu Wang
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Alzheimer’s disease
- tauopathy
- neurodegeneration
- NMR
- computational biology
- Tau
- amyloid
- structural biology
- drug discovery
- dynamics
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
