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Special Issue "Epigenetics in Cancer"
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: 30 June 2020.
Epigenetics is defined as the heritable modification of gene expression without changing the DNA sequence through processes that involve DNA methylation, chromatin remodelling and expression of regulatory RNAs. Because epigenetic modifications can be altered by external and internal environmental factors and have the ability to change gene expression, epigenetics is now considered to be an important mechanism to maintain homeostasis in the human body. Recently, it was reported that epigenetic deregulation, such as abnormal histone modifications, DNA methylation patterns and non-coding RNA expression levels, plays a critical role in human tumorigenesis. The enzyme group that controls abnormal molecular modification and non-coding RNA is considered to be an important target group for cancer treatment. In addition, advanced technologies, such as ChIP-seq, ATAC-seq, Hi-C, and ChIA-PET, have been used to unveil sophisticated chromatin regulation mechanisms, which may allow us to explore the importance of epigenetics in a systematic manner. With this Special Issue, we aim to clarify the significance of epigenetic deregulation in cancer, in particular using advanced technologies. This Special Issue will include reviews, original research articles and short contributions.
Dr. Ryuji Hamamoto
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- histone modifications
- DNA methylation
- non-coding RNA
- omics analysis
- chromatin structure analysis
- big data
- multimodal analysis