RNAs in Health and Disease: Potential Function as Biomarkers and Therapeutic Targets
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 30 November 2026 | Viewed by 37
Special Issue Editor
Interests: genomic medicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
RNA biology has progressed beyond a simple intermediary role in gene expression to become a central regulator of cellular function and disease. In addition to messenger RNAs, diverse non-coding RNAs, including microRNAs, long non-coding RNAs, and circular RNAs, play pivotal roles in controlling gene expression and maintaining physiological balance. Their dysregulation is increasingly recognized as a key driver of human disease.
Compelling evidence highlights the critical involvement of RNA networks in metabolic and cardiovascular diseases—two closely linked conditions with major global health impact. Aberrant RNA expression and function contribute to disrupted lipid and glucose metabolism, chronic inflammation, endothelial dysfunction, and cardiac remodeling. At the same time, advances in RNA-targeting approaches, such as antisense oligonucleotides, small interfering RNAs (siRNAs), and nanoparticle-based delivery systems, are rapidly expanding the therapeutic potential of RNA-based interventions. However, challenges remain in achieving efficient delivery, precise targeting, and a deeper understanding of context-specific RNA functions in complex disease settings.
This Special Issue of Biomolecules, “RNAs in Health and Disease: Potential Function as Biomarkers and Therapeutic Targets,” highlights emerging discoveries and translational advances in RNA research, with a particular focus on metabolic and cardiovascular diseases. We welcome submissions of original research and authoritative reviews addressing RNA-mediated mechanisms, biomarker development, and innovative therapeutic strategies.
We invite researchers to contribute their latest findings and perspectives to this Special Issue to advance RNA-based diagnostics and therapeutics and accelerate their translation into clinical practice.
Dr. Yei-Tsung Chen
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- non-coding RNAs
- biomarkers
- RNA therapeutics
- metabolic diseases
- cardiovascular diseases
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
