Multi-Scale Integrative Radiobiology

Dear Colleagues,

Since the discovery of X-rays, radiation biology has presented a model of multidisciplinary science in which successive events occur in various spatial and temporal dimensions. For example, the study of an individual’s response to radiation is a representative example of research involving clinical, tissue, cellular, and molecular events occurring over several days/months, hours/days, minutes/hours, seconds/minutes in metric, centimetric, micrometric, and nanometric areas. Consequently, "causal bridges" can be established between very different scales with different biomarkers to aid in observing, describing, understanding, modeling, and predicting major radiobiological phenomena.

Practically, to date we can predict a radiation-induced clinical state from molecular data, and conversely, a specific cellular death from a rigorous description of a radiation-induced tissue reaction. The papers in this Special Issue will highlight the advances made in the frame of the multiscale integrative radiobiology.

Dr. Nicolas Foray
Guest Editor

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