Post-Translational Modifications in Disease: From Computational Prediction to Functional Mechanisms
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: 31 March 2026 | Viewed by 15
Special Issue Editor
Interests: artificial intelligence-driven identification; multi-omics; tumor microenvironment; post-translationally modified
Special Issue Information
Dear Colleagues,
The functional diversity of the proteome is governed extensively by post-translational modifications (PTMs), which a dynamic repertoire which greatly expands the information encoded within the genome. PTMs—such as phosphorylation, acetylation, and ubiquitination—function as precise molecular switches that control protein stability, interactions, and localization. Dysregulation of these PTM networks is important for pathogenesis in diverse diseases, including cancer, neurodegeneration, and metabolic disorders. The emergence of cutting-edge bioinformatics has is now revealeding novel PTMs with significant pathological implications. This Special Issue will cover all a wide range of topics related to PTMs in regard to diseases. It will highlights research that bridgesing computational prediction with mechanistic validation, aiming to accelerate our understanding of disease signaling and foster the development of novel therapeutic strategies. We welcome the submission of both rReview and original research Original Research articles.
Dr. Mengsha Tong
Guest Editor
Manuscript Submission Information
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Keywords
- post-translational modifications
- PTMs
- disease
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