Combination Therapies Involving MicroRNA Modulation: Synergistic Approaches for Enhanced Anticancer Effects

Dear Colleagues,

The dynamic landscape of cancer therapeutics is undergoing a notable shift towards innovative combination therapies harnessing the potential of microRNA modulation. This Special Issue meticulously explores diverse and multifaceted strategies integrating microRNA-based interventions to achieve significantly enhanced anticancer effects. As key regulators of gene expression, microRNAs emerge as promising therapeutic targets due to their pivotal roles in tumorigenesis. Contributions within this Special Issue unveil the intricacies of microRNA-mediated pathways, emphasizing their potential as standalone agents or complementary elements to existing therapies. The exploration of synergy resulting from combining microRNA modulation with traditional chemotherapeutics, targeted therapies, and immunotherapies sheds light on novel therapeutic landscapes. The discussion also zooms in on the interplay between microRNAs and the tumor microenvironment, as well as their impact on mechanisms of drug resistance. By providing a comprehensive overview of recent advancements, challenges, and breakthroughs in the domain of combination therapies involving microRNA modulation, this Special Issue seeks to guide researchers, clinicians, and industry professionals in the development of more effective and personalized anticancer strategies. The collective insights presented herein aim to facilitate the creation of transformative approaches that enhance treatment outcomes, contributing to the ongoing evolution of cancer therapeutics.

Dr. Joanna Szczepanek
Prof. Dr. Andrzej Tretyn
Guest Editors

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• microRNA (miRNA)
• targeted therapy
• cancer