Tumour Suppressor Genes: The Guardians of Cell Integrity
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 2068
Special Issue Editor
Special Issue Information
Dear Colleagues,
Cancer remains a major threat to individuals and a major challenge to healthcare systems worldwide. Tumour suppressor genes play a pivotal role in regulating cell proliferation and preventing tumour formation. For this reason, studying their mechanism of action and defining in detail the intracellular pathways they regulate become of massive importance for implementing patients’ therapy.
This Biomolecules Special Issue explores the intricate functions and critical roles of tumour suppressor proteins in the context of cancer biology. This Special Issue will explore the diverse mechanisms through which tumour suppressor proteins regulate fundamental cellular processes. Specifically, we plan to examine the complex interplay between tumour suppressor proteins and oncogenic pathways, highlighting their significance in cancer development, progression, and therapeutic targeting.
By shedding light on the multifaceted functions of tumour suppressor proteins, this Special Issue aims to deepen our understanding of cancer pathogenesis and pave the way for novel therapeutic strategies.
Dr. Nicola Manfrini
Guest Editor
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Keywords
- cell cycle
- cell growth
- cell integrity
- cell proliferation
- DNA damage
- genome integrity
- protein homeostasis
- migration
- invasion
- metastasis
- apoptosis
- autophagy
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