Advances in Computational Biology of Intrinsically Disordered Proteins

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Bioinformatics and Systems Biology".

Deadline for manuscript submissions: 15 June 2025 | Viewed by 153

Special Issue Editor


E-Mail Website
Guest Editor
Department of Biology, McGill University, Montreal, QC, Canada
Interests: protein evolution; intrinsic disorder; compositional bias; prions; protein function

Special Issue Information

Dear Colleagues,

Bioinformatical and simulational analysis has been a key component of efforts to understand the functional and biophysical characteristics of intrinsic disorder in proteins. This Special Issue aims to bring together diverse research focuses in the computational analysis of intrinsic disorder in proteins, that produce insights and hypotheses that are actionable for future research. It is not limited to purely computational work, but may include research involving laboratory experiment.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but not limited to) the following:

  • Prediction of intrinsic disorder and its subtypes
  • Analysis of the evolution of intrinsic disorder
  • Insights into the role of compositional bias and ‘low-complexity’ sequence
  • Analysis of the function of intrinsically-disordered regions
  • Simulational analysis of intrinsic disorder
  • Computational analysis of prions
  • Computational case studies of proteins and protein families with intrinsic disorder

In this Special Issue, original research articles and reviews are welcome. I look forward to receiving your contributions.

Dr. Paul Harrison
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • intrinsic disorder
  • compositional bias
  • prions
  • protein annotation
  • protein simulation

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Published Papers

This special issue is now open for submission.
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