Non-coding RNAs in Human Diseases: Roles and Mechanisms of Action

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Genetics".

Deadline for manuscript submissions: 30 August 2024 | Viewed by 252

Special Issue Editor

E-Mail Website
Guest Editor
School of Medicine and Public Health, The University of Newcastle, Callaghan, Australia
Interests: cancer ncRNA markers for diagnosis and prognosis; regulatory networks of ncRNAs in cancer; identification of ncRNA binding partners; uncovering fundamental mechanisms of ncRNAs; pan-cancer associated ncRNAs; RNA-based therapy in cancer

Special Issue Information

Dear Colleagues,

A Special Issue on “Non-coding RNAs in Human Diseases: Roles and Mechanisms of Action” is being prepared for the journal Biomolecules.

Non-coding RNAs (ncRNAs) have revolutionized our understanding of gene regulation and cellular processes, challenging the traditional belief that only protein-coding genes are pivotal in human diseases. Their diverse roles and intricate mechanisms of action have captured the attention of researchers, illuminating their potential as valuable diagnostic markers, therapeutic targets, and prognostic indicators. This Special Issue aims to provide a comprehensive exploration of the major classes of ncRNAs, including microRNAs, long non-coding RNAs, and circular RNAs, unveiling their involvement in a broad spectrum of pathological conditions such as cancer, neurodegenerative disorders, cardiovascular diseases, and immune-mediated disorders. By delving into the underlying molecular mechanisms by which ncRNAs exert their effects, including transcriptional regulation, post-transcriptional modulation, epigenetic modifications, and intercellular communication, we seek to decipher the complex network of ncRNA-mediated interactions and their functional implications in disease pathogenesis. By inspiring further investigations into the therapeutic potential of targeting ncRNAs, this Special Issue aims to pave the way for the development of innovative treatments and precision medicine strategies, thus propelling the field forward. Original manuscripts and reviews dealing with any aspect of non-coding RNA in human disease are very welcome.

Dr. Lei Jin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • non-coding RNAs
  • human diseases
  • diagnostic markers
  • therapeutic targets
  • prognostic indicators

Published Papers

This special issue is now open for submission.
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