Molecular Biomarkers of Oxidative and Nitrosative Stress: Mechanisms, Detection, and Clinical Significance
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biomarkers".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 16
Special Issue Editors
Interests: medical biochemistry; oxidative and nitrosative stress in human pathology; redox biology; graphene derivatives; nanomedicine; drug design for cancer therapy; computational chemistry
Special Issues, Collections and Topics in MDPI journals
Interests: medical biochemistry; oxidative and nitrosative stress; free radical chemistry; redox biology; natural and synthetic antioxidants
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Oxidative and nitrosative stress in the biological system are defined as excessive production of reactive oxygen and nitrogen species (ROS/RNS) or impaired cellular antioxidant protection mechanisms contributing to aging, chronic inflammatory processes, and a broad range of pathological conditions, including metabolic disorders, neurodegeneration, cardiovascular disease, and cancer. The quantification and interpretation of selective molecular biomarkers provide a powerful scientific toolbox improving diagnostic accuracy, disease monitoring, prognosis, and evaluation of new therapeutic strategies. As our analytical capabilities continue to evolve, so does the potential for more precise detection of redox-driven biochemical alterations.
This Special Issue, “Molecular Biomarkers of Oxidative and Nitrosative Stress: Mechanisms, Detection, and Clinical Significance” aims to collect high-quality research dedicated to the identification, validation, and mechanistic interpretation of biomarkers associated with redox disturbances in the biological system. In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:
- Novel analytical methodology for detecting oxidation and nitration products of biomolecules;
- Mechanistic studies on oxidative and nitrosative stress affecting cellular signaling pathways;
- Biomarker applicability in cellular biochemistry, in vivo studies or clinical models;
- Translational studies focusing on diagnostic and prognostic significance of oxidative and nitrosative stress biomarkers in human pathology.
We look forward to receiving your contributions.
Dr. Narcyz Knap
Prof. Dr. Michał Woźniak
Guest Editors
Manuscript Submission Information
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Keywords
- oxidative stress
- nitrosative stress
- reactive oxygen species (ROS)
- reactive nitrogen species (RNS)
- lipid peroxidation
- ferroptosis
- protein oxidation
- DNA oxidative modifications
- antioxidant defense mechanisms
- free radicals
- redox signaling
- redox biomarkers
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