Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.2
3.9
Journals
Biomimetics
Special Issues
3D Bio-Printing for Regenerative Medicine Applications
share announcement

3D Bio-Printing for Regenerative Medicine Applications

A special issue of Biomimetics (ISSN 2313-7673). This special issue belongs to the section "Biomimetic Design, Constructions and Devices".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 2434

Special Issue Editors

Dr. Lukasz Witek

E-Mail Website
Guest Editor
1. Biomaterials and Regenerative Biology Division, NYU College of Dentistry, New York, NY 10010, USA
2. Department of Oral and Maxillofacial Surgery, NYU College of Dentistry, New York, NY 10010, USA
3. Department of Biomedical Engineering, NYU Tandon School of Engineering, Brooklyn, NY 11201, USA
4. Hansjörg Wyss Department of Plastic Surgery, NYU Grossman School of Medicine, New York, NY 10016, USA
Interests: 3D printing; additive manufacturing; bioceramics; biomaterials; implants; scaffolds; tissue engineering; bone healing
Dr. Vasudev Vivekanand Nayak

E-Mail Website
Guest Editor
Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
Interests: biomaterials; additive manufacturing

Special Issue Information

Dear Colleagues,

The field of additive manufacturing/3D printing is/has been rapidly evolving and with its integration into/with regenerative medicine, it represents a groundbreaking advancement, particularly for the development of resorbable scaffolds. These scaffolds play a crucial role in tissue engineering by providing structural support and facilitating cellular activity necessary for tissue regeneration. Ceramics and polymers, known for their biocompatibility, stability, and ability to successfully integrate with biological tissues, offer unique advantages for creating scaffolds tailored to specific applications/defects.

This Special Issue delves into the latest research and innovations in 3D-printed scaffolds, exploring diverse fabrication techniques, material compositions, and design strategies. This Special Issue aims to highlight the potential of these scaffolds in various regenerative medicine applications, including bone and cartilage repair, as well as their role in overcoming the current challenges in the field. Through a collection of original research articles and reviews, we seek to provide a comprehensive overview of the current state of research, emerging trends, and future directions, fostering collaboration and inspiring new approaches in the pursuit of effective regenerative therapies.

Dr. Lukasz Witek
Dr. Vasudev Vivekanand Nayak
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomimetics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • 3D printing scaffolds
  • biofabrication techniques
  • material compositions
  • regenerative medicine

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Review

15 pages, 2908 KB  
Article
Bioinspired Design of Ergonomic Tool Handles Using 3D-Printed Cellular Metamaterials
by Gregor Harih and Vasja Plesec
Biomimetics 2025, 10(8), 519; https://doi.org/10.3390/biomimetics10080519 - 8 Aug 2025
Viewed by 548
Abstract
The design of ergonomic tool handles is crucial for user comfort and performance, yet conventional stiff materials often lead to uneven pressure distribution and discomfort. This study investigates the application of 3D-printed cellular metamaterials with tunable stiffness, specifically gyroid structures, to enhance the [...] Read more.
The design of ergonomic tool handles is crucial for user comfort and performance, yet conventional stiff materials often lead to uneven pressure distribution and discomfort. This study investigates the application of 3D-printed cellular metamaterials with tunable stiffness, specifically gyroid structures, to enhance the ergonomic and haptic properties of tool handles. We employed finite element analysis to simulate finger–handle interactions and conducted subjective comfort evaluations with participants using a foxtail saw with handles of varying gyroid infill densities and a rigid PLA handle. Numerical results demonstrated that handles with medium stiffness significantly reduced peak contact pressures and promoted a more uniform pressure distribution compared to the stiff PLA handle. The softest gyroid handle, while compliant, exhibited excessive deformation, potentially compromising stability. Subjective comfort ratings corroborated these findings, with medium-stiffness handles receiving the highest scores for overall comfort, fit, and force transmission. These results highlight that a plateau-like mechanical response of the 3D-printed cellular metamaterial handle, inversely bioinspired by human soft tissue, effectively balances pressure redistribution and grip stability. This bioinspired design approach offers a promising direction for developing user-centered products that mitigate fatigue and discomfort in force-intensive tasks. Full article
(This article belongs to the Special Issue 3D Bio-Printing for Regenerative Medicine Applications)
►▼ Show Figures

Figure 1

12 pages, 2351 KB  
Article
Effects of Extrusion Pressure During 3D Printing on Viability of Human Bronchial Epithelial Cells in 3D Printed Samples
by Taieba Tuba Rahman, Nathan Wood, Zhijian Pei, Hongmin Qin and Padmini Mohan
Biomimetics 2025, 10(5), 297; https://doi.org/10.3390/biomimetics10050297 - 8 May 2025
Viewed by 610
Abstract
This study investigates how different levels of extrusion pressure during 3D printing affect the cell viability of human bronchial epithelial (HBE) cells embedded in printed samples. In this study, samples were printed at three levels of extrusion pressure. The cell viability was assessed [...] Read more.
This study investigates how different levels of extrusion pressure during 3D printing affect the cell viability of human bronchial epithelial (HBE) cells embedded in printed samples. In this study, samples were printed at three levels of extrusion pressure. The cell viability was assessed through live/dead staining via microscopic imaging. The results show that increasing the extrusion pressure from 50 to 100 kPa led to a higher degree of cell death. These results demonstrate how the extrusion pressure affects the viability of HBE cells and provide a basis for future studies on pressure-induced responses in respiratory tissues. Full article
(This article belongs to the Special Issue 3D Bio-Printing for Regenerative Medicine Applications)
►▼ Show Figures

Figure 1

Review

Jump to: Research

29 pages, 3233 KB  
Review
A Comprehensive Review on Bioprinted Graphene-Based Material (GBM)-Enhanced Scaffolds for Nerve Guidance Conduits
by Siheng Su and Jilong Wang
Biomimetics 2025, 10(4), 213; https://doi.org/10.3390/biomimetics10040213 - 31 Mar 2025
Viewed by 887
Abstract
Peripheral nerve injuries (PNIs) pose significant challenges to recovery, often resulting in impaired function and quality of life. To address these challenges, nerve guidance conduits (NGCs) are being developed as effective strategies to promote nerve regeneration by providing a supportive framework that guides [...] Read more.
Peripheral nerve injuries (PNIs) pose significant challenges to recovery, often resulting in impaired function and quality of life. To address these challenges, nerve guidance conduits (NGCs) are being developed as effective strategies to promote nerve regeneration by providing a supportive framework that guides axonal growth and facilitates reconnection of severed nerves. Among the materials being explored, graphene-based materials (GBMs) have emerged as promising candidates due to their unique properties. Their unique properties—such as high mechanical strength, excellent electrical conductivity, and favorable biocompatibility—make them ideal for applications in nerve repair. The integration of 3D printing technologies further enhances the development of GBM-based NGCs, enabling the creation of scaffolds with complex architectures and precise topographical cues that closely mimic the natural neural environment. This customization significantly increases the potential for successful nerve repair. This review offers a comprehensive overview of properties of GBMs, the principles of 3D printing, and key design strategies for 3D-printed NGCs. Additionally, it discusses future perspectives and research directions that could advance the application of 3D-printed GBMs in nerve regeneration therapies. Full article
(This article belongs to the Special Issue 3D Bio-Printing for Regenerative Medicine Applications)
►▼ Show Figures

Graphical abstract

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-3
Back to TopTop