Special Issue "Sepsis: Diagnostics and Therapeutics"

A special issue of Biomedicines (ISSN 2227-9059).

Deadline for manuscript submissions: 31 July 2020.

Special Issue Editors

Prof. Tsukasa Nakamura
Guest Editor
Division of Nephrology, Department of Medicine Shinmatsudo Central General Hospital, Japan
Interests: sepsis; critical care medicine; renal replacement therapy; LDL-apheresis; diabetic nephropathy
Special Issues and Collections in MDPI journals
Dr. Eiichi Sato

Guest Editor
Division of Nephrology, Department of Medicine Shinmatsudo Central General Hospital, Japan
Interests: sepsis; acute kidney injury; chronic kidney disease; hemodialysis therapy; diabetic nephropathy; Aquaporin 2
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

The recently-modified Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) defines sepsis as a “life-threatening organ dysfunction caused by a dysregulated host response to infection” and septic shock as “a subset of sepsis in which particularly profound circulatory, cellular, and metabolic abnormalities are associated with a greater risk of mortality than with sepsis alone”. Sepsis-3 guidelines still prompt debate and discussion, such as the requirement for a serum lactate level to diagnose septic shock, or use of the quick sepsis-related organ failure assessment (SOFA) score in the diagnosis of sepsis. Further detailed verification is required for reevaluation and future revision of Sepsis-3.

This Special Issue of the Biomedicines will focus on sepsis, and report new insights into epidemiology, pathophysiology, diagnosis, biomarkers, and treatment. In addition, other morbidities and renal replacement therapy, including acute kidney injury and hemodiafiltration, are associated with sepsis, and submissions dealing with these conditions are welcome.

This Special Issue is jointly organized between IJMS and Biomedicines journals. According to the Aims and Scope of these journals, articles showing basic studies in biochemistry, molecular biology, and molecular medicine can be submitted to IJMS, while articles presenting more clinical content can be submitted to Biomedicines.

Prof. Tsukasa Nakamura
Dr. Eiichi Sato
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Sepsis-3
  • infection
  • septic shock
  • SOFA
  • organ dysfunction
  • acute kidney injury
  • renal replacement therapy
  • hemodiafiltration
  • biomarkers
  • therapeutics

Published Papers

This special issue is now open for submission.
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