Special Issue "Diabetes Complications: From Pathophysiology to Novel Therapeutic Approaches"

A special issue of Biomedicines (ISSN 2227-9059).

Deadline for manuscript submissions: 31 July 2020.

Special Issue Editor

Dr. Istvan Kovanecz
Guest Editor
1. The Lundquist Institute, Torrance, CA, USA;
2. David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
Interests: diabetes-related complications; metabolic syndrome; sexual dysfunction; urinary incontinence; cardiac-, skeletal- and smooth muscle regeneration; stem cell and gene therapy

Special Issue Information

Dear Colleagues,

The Special Issue, “Diabetes Complications: From Pathophysiology to Novel Therapeutic Approaches”, will focus on the molecular pathophysiology of diabetes mellitus and its devastating complications, as well as new biomarkers for early detection, and novel therapeutic approaches.

Diabetes mellitus has become a worldwide epidemic in recent decades. A global survey estimated more than half a billion cases of T2DM in 2018, and the number is rapidly rising. Long-term complications of T2DM cause a wide range of increasingly prevalent debilitating co-morbidities with complex pathophysiology in diabetic patients. A more comprehensive understanding of the underlying molecular processes and identification of key molecules could lead to a more precisely targeted intervention either for prevention or for treatment. Monitoring changes in the global gene expression profile, refined by global micro RNA expression profiling, could provide the necessary clues to find those key components and biomarkers. This Special Issue is open for original articles and reviews in basic, clinical, and translational, as well as multidisciplinary research, including but not limited to the following diabetes-related topics:

  • Cardiovascular disease
  • Hyperlipidemia
  • Neuropathy
  • Erectile dysfunction
  • Nephropathy
  • Retinopathy
  • Skin conditions
  • Impaired wound healing
  • Hearing impairment
  • Psychological effects

Dr. Istvan Kovanecz
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • diabetes complications
  • epigenetic imprinting
  • molecular profiling
  • biomarkers
  • targeted therapy
  • glucose control
  • conventional and complementary approaches
  • stem cell damage
  • vascular damage and regeneration

Published Papers

This special issue is now open for submission.
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